I am 54 years old (55 in August) recently moved to Spain and have been taking Meriestra (estradiol valearate) 1mg (oral) and Darstin gel which I am to use twice a day 2.5 g each time morning and night for 12 days per month as I still have my uterus. The Meriestra has helped immensely with the vaginal atrophy that I was suffering, but the Darstin seems to do nothing at all!! The hot flashes are worst than ever but I am determined to stick with it for the sake of my VA relief. Can you give me any advice? Have looked all over the tube, packet and info leaflet but cannot find any info regarding progesterone percentage so don't know whether to increase, decrease or what to do for the best! Have asked at the pharmacy where I bought the Darstin but they just tell me to follow the twice a day regime which I am doing! Any help/advice would be greatly appreciated.