Progesterone Blog

May 10, 2025

Progesterone and oral health during menopause

I am interested in finding out if there are any benefits from progesterone cream for oral health in menopause. The articles I have read mention synthetic

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Apr 25, 2025

Confused about blood test results

Hello, I have recently had blood tests done for estradiol and progesterone on day 5 of my cycle on April 16. i am definitely in perimenopause the last

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Apr 23, 2025

Upping the dose for progesteone Therapy?

Unfortuantely I just posted my qustion under someone else's question. I do apologise as it shouldn't have gone there, so I'll write it here under a new

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Apr 22, 2025

​Exhausted from insomnia caused by night sweats

At 34 I lost my first pregnancy due to water breaking at 16 weeks. Second pregnancy required trans-abdominal-cerclage(TAC) placed by surgery at 19 weeks.

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Apr 14, 2025

Dosage of progesterone for anxiety

I had a hysterectomy a year ago and have been on 1/2 to 1/4 teaspoon progesterone cream, twice a day. No other hormones, only supplements. I am post menopausal

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Mar 29, 2025

No period after 14 days of progesterone

Hi, I have been taking Ona’s 20% 100mg x 2 daily. I’ve had lots of issues that have been on going since having the copper iud (now removed) when I had

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Mar 27, 2025

Progesterone withdrawal?

I have been on progesterone for close to three years now (and recently have went off of it). I was taking 75mg (but was having weird symptoms and found

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Mar 21, 2025

Colposcopy

Almost 40 on 200mg progesterone for close to a year with magnesium, d3 and k. Had abnormal pap recently and they want colposcopy—- now suddenly bleeding

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Mar 19, 2025

HRT active ingredients

HRT active ingredients, hormone replacement therapies

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Mar 03, 2025

Treatment for Postpartum Anxiety/Depression/OCD

I have found this website after a deep dive into progesterone as treatment for postpartum mental health disorders and an so grateful for all the information

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Feb 28, 2025

Perimenopause and Insomnia

Hello, I'm 51 and have had very irregular cycles for last 2 years and during this time some very heavy/long bleeds. Also many cycles way too short. Started

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Feb 21, 2025

Breast cancer

My mom died of breast cancer and my aunt has it …I have some Lumps in my breast I got checked today and the gyno said she wasn’t crazy about me using progesterone

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Feb 16, 2025

Why would progesterone shrink small but not large fibroids?

Hello, I am 56 year old and have a large 13 cm uterine fibroid. Reading about progesterone therapy, I would really like to try it..Many comments state

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Jan 22, 2025

Castor Oil

I've been using 200mg progesterone cream for probably almost a year now. I still seem to have some estrogen dominance....I also supplement with vitamin

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Jan 14, 2025

Adenomyosis fibroid, polyp, Dr. Prescribed Biest w/ progesterone?

I am 49 and have been suffering with extremely heavy periods for 9 years. I also have a huge list of perminopausal/Estrogen dominent symptoms - very sore

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Jan 12, 2025

Would you trust this brand of bio identical progesterone?

I am confused as I can’t find the company’s website or contact number. I asked in the estrogen dominance support Facebook group, and some people thought

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Jan 07, 2025

New Stabilising Agent

The stabilising agent in our new Natpro tubes ‘dehydroxanthan gum’ has been changed to ‘Xanthan Gum (and) Lecithin (and) Sclerotium Gum (and) Pullulan)’

Patented optimised combination of phospholipids and polysaccharides, this is a natural stabiliser gelling agent that leaves an amazing silicone-like skin feel.

It is a preservative-free, ecofriendly, foolproof gelling agent with amazing silicone-like skin feel & texture and 100% natural origin. Also, serves as a thickener, co-emulsifier, stabilizer, suspending agent and skin feel enhancer. This green processed ingredient shows high compatibility with electrolytes.

This senso-active functional ingredient improves active ingredient efficacy and offers skin hydration for true active textures. It provides softness properties demonstrating highly attractive sensory identity. It brings hydration for a 100% active base and reinforces the protective barrier which decreases TEWL and therefore helps keep the skin moisturized.

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Dec 19, 2024

Katie

ENDOMETRIAL HYPERPLASIA. Has anyone successfully treated this condition with progesterone cream with lasting effects? I am booked for a hysterectomy so

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Dec 15, 2024

Itchiness and Psoriasis on legs

I'm 46, have used 400mg of natpro daily for many months now (I live in extreme stress due to personal circumstances), and only in the luteal phase for

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Dec 10, 2024

Sodium Olivoil Glutamate

The emulsifier in our new Natpro 60ml tubes remains olive oil based but has been changed from ‘cetearyl olivate/sorbitan olivate’ to ‘sodium olivoil glutamate'.

Sodium OLIVOIL Glutamate is a non-ethoxylated, vegetal derived surfactant that combines the unique fatty acid profile of olive oil with the characteristic affinity of glutamic acid toward the skin surface.

The quest for PEG-free emulsifiers led to the creation of new classes of base ingredients, one of which is this skin-friendly and environmentally-friendly Sodium OLIVOIL Glutamate.

This new emulsifier structure provides:

•high skin compatibility.•suitable for sensitive skin as well as babies or children’s skin.•protecting, soothing and restoring functionality.•maximum biodegradability according to the CEE regulation N.82/242 OECD Method.

As the whole concept of creating a more efficient equilibrium between ones skin and ones body has increased in popularity, we are seeing an increased success with ingredients of natural origin, embracing the concepts of respect for your skin, or skin friendly emulsifiers.

This is due to 2 main aspects:

1. The need for developing formulas as much as possible compatible with the physiology of skin and its annexes, without any adverse effect or allergic potential.

2.The growing confidence of consumers in the beneficial properties provided by complex mixtures of natural ingredients.

Visit our store at Organic Products.

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Dec 10, 2024

Sodium Olivoil Glutamate

The emulsifier in our new Natpro 60ml tubes remains olive oil based but has been changed from ‘cetearyl olivate/sorbitan olivate’ to ‘sodium olivoil glutamate'.

Sodium OLIVOIL Glutamate is a non-ethoxylated, vegetal derived surfactant that combines the unique fatty acid profile of olive oil with the characteristic affinity of glutamic acid toward the skin surface.

The quest for PEG-free emulsifiers led to the creation of new classes of base ingredients, one of which is this skin-friendly and environmentally-friendly Sodium OLIVOIL Glutamate.

This new emulsifier structure provides:

•high skin compatibility.•suitable for sensitive skin as well as babies or children’s skin.•protecting, soothing and restoring functionality.•maximum biodegradability according to the CEE regulation N.82/242 OECD Method.

As the whole concept of creating a more efficient equilibrium between ones skin and ones body has increased in popularity, we are seeing an increased success with ingredients of natural origin, embracing the concepts of respect for your skin, or skin friendly emulsifiers.

This is due to 2 main aspects:

1. The need for developing formulas as much as possible compatible with the physiology of skin and its annexes, without any adverse effect or allergic potential.

2.The growing confidence of consumers in the beneficial properties provided by complex mixtures of natural ingredients.

Visit our store at Organic Products.

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Dec 06, 2024

how to know when to increase or decrease

Good day. I have been using Natpro for a couple of years. I am post menopausal. I was on HRT for 7 years. 2 years ago I started by replacing the progesterone

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Dec 04, 2024

We have added nicotinamide (vitamin B3)!

🌿We have added ‘nicotinamide’ (vitamin B3) to our trusted formula in our New 60ml Tubes!

🌿Read on to discover the benefits...

Nicotinamide, also known as niacinamide, is a form of vitamin B3 that offers numerous benefits for skin health.

Key Benefits of Nicotinamide for Skin:

🌱 Enhances Skin Barrier Function... Nicotinamide helps build keratin, a protein essential for maintaining skin health. It strengthens the skin's lipid barrier, which locks in moisture and protects against environmental irritants, making it beneficial for all skin types, particularly those with conditions like eczema and rosacea.

🌱 Reduces Inflammation... This ingredient is known for its anti-inflammatory properties, which can help calm redness and irritation associated with acne, rosacea, and other inflammatory skin conditions. By reducing inflammation, nicotinamide can improve overall skin tone and texture.

🌱 Minimizes Pore Appearance... While it does not physically reduce pore size, nicotinamide can help minimize their appearance by keeping the skin smooth and regulating oil production, which prevents clogged pores and breakouts.

🌱 Treats Acne... Nicotinamide has been shown to be effective in treating acne vulgaris. Clinical studies indicate that topical nicotinamide gel can be as effective as traditional topical antibiotics in reducing acne lesions. Additionally, it decreases sebum production, which contributes to acne development.

🌱 Addresses Hyperpigmentation... Research suggests that formulations containing 5% nicotinamide can lighten dark spots and improve skin tone over time. This effect is attributed to increased collagen production and improved skin texture.

🌱 Protects Against Sun Damage... Nicotinamide enhances the skin's ability to repair DNA damage caused by UV exposure and may reduce the risk of certain types of skin cancer in high-risk individuals. However, it should not be used as a substitute for sunscreen.

🌱 Reduces Fine Lines and Wrinkles... Topical application of nicotinamide has been linked to improvements in fine lines and wrinkles due to its ability to stimulate collagen production and improve skin elasticity. Studies have reported significant improvements in signs of aging after consistent use over several weeks.

🌱 Increases Hydration... Nicotinamide helps reduce transepidermal water loss (TEWL), thereby increasing hydration levels in the upper layers of the skin. This makes it particularly beneficial for dry or dehydrated skin types.

Natpro Tube

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Dec 03, 2024

Cream Percentages

It is important to know the percentage of progesterone in the cream you choose to use...

You will be administering a different quantity of progesterone per gram of cream depending on the percentage strength of the progesterone in the cream.

For example Natpro is a 3.33% cream which means it has a concentration of 3333mg of progesterone. So for every gram of Natpro cream you are getting 33.33mg of progesterone.

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Nov 28, 2024

Natpro Black Friday Sale!!

Just in time for Black Friday!

15% off our New Natpro Tube!

To take advantage of this launch offer please copy this coupon code…

natpro15

…then paste it into the ‘coupon code’ field on the order form after you click the ‘Add to Cart’ button.

The coupon is valid right now and expires midnight Saturday 30th November.

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Nov 27, 2024

NEW Natpro 60ml Tubes!!

🌿Reintroducing the Natpro 60ml Tubes!🌿

Due to countless requests for our tube option we are very happy to announce that we have brought it back into the Natpro family!

Not only are we re-launching it right now but we have introduced three modifications to the long established Natpro formula each of which bring small but meaningful improvements enhancing efficacy without changing the concentration of natural progesterone which remains at 3.33%.

Here are the modifications…

1• The emulsifier remains olive oil based but has been changed from ‘cetearyl olivate/sorbitan olivate’ to ‘sodium olivoil glutamate’

2• The stabilising agent ‘dehydroxanthan gum’ has been changed to ‘Xanthan Gum (&) Lecithin (&) Sclerotium Gum (&) Pullulan)’

3• We have added ‘nicotinamide’ (vitamin B3)

Read up on our formula modifications here.

Thank you for your continued support, we look forward to your feedback on the new tube!

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Nov 18, 2024

Sleep deprived and miserable!

Hello, I have struggled with sleep issues for over 15 years. I can get to sleep fine, but I often wake up in the middle of the night and can't get back

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Nov 05, 2024

Natpro Stock In! 10% discount

To our dear customers

As you may know we were stocked out of our Natpro dispenser for several days due to shipping delays so...

To compensate for the inconvenience and thank you for your loyalty and patience please use this coupon...

natpro10

...to claim your 10% discount on Natpro progesterone cream. Simply copy the coupon above and paste it into the coupon field after clicking the 'Add to Cart' button here...

Click here to claim your 10% now

•Offer is not limited by number of units per order.

•Offer expires midnight 19th November 2024.

Thank you and to your good health!

Organic Products & the Progesterone Therapy team

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Oct 24, 2024

What about Progestelle? I used to purchase it here as the "gold standard"?

Hello again after a few years. When I first found this lovely sight years ago, Progestelle was available for purchase as a gold standard due to the simple

Continue reading "What about Progestelle? I used to purchase it here as the "gold standard"?"

Oct 17, 2024

Understanding the Role of Progesterone in Managing Cortisol Levels in Children

Recent research highlights the substantial role of progesterone in managing cortisol levels, particularly in children, and even more specifically, in boys. Cortisol, recognized as the "stress hormone," significantly impacts children's behavior and stress levels, as demonstrated by hair cortisol concentration (HCC) studies. HCC offers a long-term perspective on cortisol levels, unlike blood or saliva tests that only reflect short-term fluctuations.

A study conducted on 11-year-olds in Spain revealed that higher HCC is associated with increased behavioral issues. This finding is particularly prominent in boys, suggesting a sex-specific susceptibility to stress-induced behavioral problems. These problems correlate with environmental stressors like noise and familial stress, particularly maternal stress, which in turn elevates cortisol levels in children.

Excess cortisol due to chronic stress can cause various negative health impacts. Therefore, maintaining balanced cortisol levels is crucial, and this is where progesterone plays a vital role. Progesterone is a naturally occurring hormone known for its anti-cortisol and anti-adrenaline properties. It directly counters cortisol's effects, offering a natural solution to lower these harmful levels, thereby reducing stress symptoms and enhancing overall well-being.

Progesterone works by enhancing the activity of GABA (gamma-aminobutyric acid), a key neurotransmitter that promotes relaxation and reduces anxiety, creating a calming effect. Furthermore, progesterone helps regulate the adrenal glands' activity, ensuring a balanced production of stress hormones like cortisol and adrenaline. Improving sleep quality is another benefit of progesterone, important for managing healthy cortisol rhythms and reducing stress.

These benefits of progesterone can be particularly helpful for children experiencing stress and related behavioral issues. By optimizing progesterone levels, reductions in anxiety, improvement in mood stability, fewer mood swings, and better sleep quality can be achieved when cortisol levels are managed effectively.

Using progesterone must be done under medical supervision to ensure proper dosing. It's crucial to integrate progesterone use with a comprehensive health strategy, which includes maintaining a balanced diet, regular physical activity, and incorporating stress-reduction practices like mindfulness or meditation.

In conclusion, progesterone stands as a promising tool in managing cortisol levels and mitigating its adverse effects on stress and behavior, particularly in boys. Its ability to balance stress responses highlights its importance in any holistic approach to children's well-being amidst the complexities of modern environmental and social stressors.

Reference:

Hair cortisol determinants in 11-year-old children: Environmental, social and individual factors

Analysis by Dr. Joseph Mercola: Is Elevated Cortisol Affecting Your Child's Behavior?, 9th October 2024