Hi Christina Although we give a shelf life of 18 months, it does last 2 years. The progesterone will be unaffected, it's only the possibility the cream might be rancid. But you'll notice if it is once opened. if you need info on How to use progesterone cream, please read through this page. Take care Wray
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Although this web site is not intended to be prescriptive, it is intended, and hoped, that it will induce in you a sufficient level of scepticism about some health care practices to impel you to seek out medical advice that is not captive to purely commercial interests, or blinded by academic and institutional hubris. You are encouraged to refer any health problem to a health care practitioner and, in reference to any information contained in this web site, preferably one with specific knowledge of progesterone therapy.