Progesterone trial for severe PMDD after GnRH treatment, mirenas etc
I'm 40 and have been in an out of gynaes for over 20 years for PMDD and suspected endo. I've endured all manner of treatments, in the early days having one of the first Mirenas fitted and using estrogen patches to trick the body into menstruation. I've been on Prozac for 15 years and also tried taking it for the recommended luteal phase with no difference. For the last 6 years I've had first 3 years on GnRH analogue treatment with add back HRT, a break followed by severe return of symptoms and a return to the GnRH suppression treatment until now. Although I have had a good result of no premenstrual cycle as I have no cycle, I have had side effects of the suppression treatment .... bone/ joint pain, weight gain, exhaustion and general malaise (all similar to the PMS itself but without the severe pelvic and breast pain)I was given tubes of testosterone gel to counter tiredness but not sure they helped.
Where I am now - moved to another country and consulted with new gynaes. Here they do not prescribe the suppression treatment long term for longer than 4 injections, mainly for IVF (regardless of add back HRT for bone mineralization) They do not give Mirena to women who have not had children and they don't perform hysterectomies on women until late 40s/50.
What they have given me is a tube of Progestogel and told me that here they use this!
Given no alternative ... I will now try progesterone! Currently I am still in ovarian suppression as seen on MRI but 3 days of progesterone and feeling those familiar heavy, dragging cramps. Question - Should they have prescribed a progesterone whilst I have a mirena?
Anyway, this is a story in motion as I need to return to MY normality of the painful cycles I had previously to begin this progesterone regimen.
I've tried countless, nutritional and herbal supplements over the years with no relief.
I am now sticking with vit D oral spray and transderm magnesium.