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How to use the progesterone cream

by Cathy
(Australia)

Hi Wray, I saw a question from one of your readers asking about the latest Dr Mercola information advising people to use progesterone cream in the vagina to stop the build up in fat cells.

I was wondering if you had any more details on this. Excuse the following personal question but I'm sure others would like to know too. If you have a cream and not pills do you try and get the cream right into the vagina somehow or just rub it inside the vaginal lips?? I'm not exactly sure how to administer the cream based on what he said.

Any info would be great. Thanks.

Comments for How to use the progesterone cream

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May 09, 2011
 How to Use in Vagina
by: Anonymous

Yes I would like to know also, have read recommendations to apply vaginally but with no instruction.

May 09, 2011
 application
by: Anonymous

I also would like a clear answer for this as this could be revolutionary. Wouldn't the vagina area become saturated by the progesterone just as other parts of the body do?
May 10, 2011
 How to use progesterone (reply)
by: Gina

I found this info on another page in this site:

Progesterone application methods.
May 11, 2011
 How to use the progesterone cream
by: Wray

Hi Cathy Dr Mercola does advocate using it in the vagina in preference to the skin. But in the 15 years I've used it, and advised on it's use, I've not found this a problem, either in myself or others. In fact if I do go through extra stress I cover myself with the cream, including in the vagina. In fact I put some there every night. I do this for a couple of days till I feel 'topped' up. I find the symptom which comes back most readily is labile emotions. Last year I had a great deal of stress, nothing serious, just more of the usual daily stressors, plus working long hours. I used 2tsp per day, which gave me 330mg/day progesterone. I did this for 2 weeks, and during that time I suffered bad oestrogen dominance. I ached in every muscle, joints too, I felt so old! Plus I was not pleasant to be around. My nails had become very weak too, splitting and flaking off. Well at the end of the 2 weeks, I had my strong nails back again, and not an ache left. I normally use about 170mg/day progesterone (1tsp cream), so I think I can safely say my receptors are working fine still! I would not have had the Oestrogen Dominance if they had been turned off by too much progesterone. Or it had saturated the cells. See these papers here and here. Applying the cream in the vagina can be done using a finger or putting the cream in a syringe. Take care Wray
May 11, 2011
 what to do????
by: Anonymous

Hello Wray, I find that I'm having spotting three weeks out of the month when I apply internally, I feel cramps and have dried blood and blood. My dr says that the progesterone is building up and that is causing the bleeding...?? I still feel cruddy and I don't know what to do. I'm. Taking my supplements and I'm under heavy stress. I have adrenal exhaustion as well! My hair seems to be coming out again as well!!!!. I get my results for my test again today. I will see what they are.

Thank you for your helpful site! !!!!;).
May 16, 2011
 what to do????
by: Wray

Hi there I'm not sure how much progesterone you're using, but if you're having spotting for 3 weeks out of every month, it appears far too little. I recommend 100-200mg/day, dependant on symptoms. Progesterone doesn't cause bleeding, in fact it stops it! MMP's cause bleeding, these are enzymes that break down protein. They play a role in the breakdown of endometrial tissues at the end of the menstrual cycle. Oestrogen stimulates MMPs. Progesterone suppresses MMPs. It?s only when progesterone levels drop at the end of the cycle that the MMP?s can get to work, and break down the lining causing our monthly bleed. If there is sufficient oestrogen in the body it will stimulate more lining, and so the cycle goes, see here and here. But if progesterone is low due to anovulation, spotting and/or bleeding can continue. Please consider increasing the amount of progesterone you are using, for more info see How to use progesterone cream. But before you do please see our page on Oestrogen Dominance. It's really not essential to use progesterone in your vagina, it's an option. It's certainly good for dryness and inflammation if that's a problem. I've found supplemental progesterone excellent for adrenal stress. The adrenals first make progesterone which they then convert into cortisol. If they are under stress they'll rob other sources, notably the ovaries. This then effects the reproductive cycle, in fact stress causes anovulation, which of course means no progesterone is made. A vicious cycle. Progesterone does help hair, but so do many nutrients. I'm running out of space so will start a new comment below. Take care Wray
May 23, 2011
 Vaginal use
by: Wray

Hi there I've had a rash of queries asking about vaginal use, it seems to be the in place to use it. And yet Dr Dalton was prescribing progesterone pessaries to her patients 60 years ago, so there's nothing new about it at all. The rectum is another place it can be applied, suppositories are normally given for this. Although there is no difference in composition between a pessary and a suppository, only the name varies. The cream can be applied in the vagina with either with a finger or syringe, there are also fizzy vaginal tablets too. I can't say I relish the thought of those! We do have a page on Delivery systems which gives all the options. Take care Wray
May 23, 2011
 Fatty tissue
by: Wray

Hi there The vagina has no fatty tissue, as does the skin. So the reasoning goes there can't be a build up there. But as progesterone is so beneficial if applied directly to the skin, it seems a waste not to use it there. I've found that it's effect is far quicker too, then waiting for it to circulate. For instance for aches and pains, it's the best thing for burns, it soothes immediately, excellent for piles if applied directly to them, minor cuts and bruises, leg ulcers and more. It's excellent for the face too, see here. Take care Wray
May 23, 2011
 Part 2 to 16 May post
by: Wray

Hi there Please consider taking 5000iu's/day vitamin D, 2000mg/day N-actyl cysteine, 2000mg/day inositol, 2-3mg biotin and 100mg thiamine (B1). Please check your iron levels, and there is some evidence the amino acid lysine is beneficial too, see here. Vitamin D is vital for the anagen phase of hair growth, see here, here and here. Please consider having a test done, for more info see the Vitamin D council and GrassrootsHealth websites. Thanks for the kind words! Take care Wray
Oct 04, 2011
 Insomnia
by: Sandra

I read Dr Mercolas article about applying progesterone cream in the vagina. I am interested because I know I have low progesterone from a saliva test. I also have insomnia. I fall asleep easy but wake up after 4-5 hrs and cannot go back to sleep. When I take progesterone cream applied to the skin it wires me and I cannot fall asleep as I usually do, and I have a much worse night of sleep, which is normally not good anyway. It doesn't matter if I apply it morning or night. I get that wired effect. I first applied the cream transdermally about 8yrs ago and it worked nicely for several months (I lost weight and I slept better), but after that I noticed it affected my sleep and I was gaining weight. I was hoping applying the progesterone cream in the vagina, it would take a different route and work better.

Wray, any comments from you about why the progesterone cream causes me to feel wired would be appreciated. It seems it causes my cortisol to rise. Thanks.
Oct 06, 2011
 Insomnia
by: Wray

Hi Sandra The vagina is a good place to apply progesterone, particularly for dryness or inflammation. It's also helpful for Candida. But it matters not where you put it, on the skin, in the vagina, nose, ears, it travels rapidly around the body, carried on red blood cells. The vagina has an ample supply of blood vessels, so it enters the circulation very quickly. The wired feeling was an Oestrogen Dominance symptom, you were evidently using too little progesterone. Perhaps the 20-40mg/day most people recommend? I suggest using 100-200mg/day, more if symptoms are severe. We do have further info on our page How to use progesterone cream. Progesterone is excellent for sleep, see here. It's essential to make progesterone the dominant hormone, it's only possible to do this by using high amounts. So if you should consider using it again, please make sure you use sufficient. I prefer the cream, but there are other Delivery systems you might like to look at. If enough progesterone is used it suppresses cortisol, which incidentally is made from progesterone within the adrenals. Stress causes cortisol to rise, stress also drops progesterone levels, simply because it's being converted to cortisol. So given sufficient supplemental progesterone, the stress effect is lessened and cortisol drops. In fact progesterone is an excellent anxiolytic, see here, here and here. Take care Wray
Dec 05, 2012
 progesterone
by: Anonymous

hi there can this also help with Pcos, im not sure what dosage I should use for that was goering you head some better info.
Dec 06, 2012
 progesterone
by: Wray

Hi there Progesterone can help PCOS, but not alone. Large amounts of antioxidants are needed too to reverse the PCOS. The page I've given you gives a list of these, and how much progesterone is needed. We also have more general info on our page How to use progesterone cream. Please have a vitamin D test done, as this is often low in PCOS. For more info on vitamin D levels, test kits etc see the Vitamin D Council, GrassrootsHealth and Birmingham Hospital. Blood levels should be 70-100ng/ml (175-250nmol/L) and not the 30ng/ml (75nmol/L) most labs and doctors regard as adequate. The minimum daily dose should be 5000iu's per day, although recent research indicates it should be 10,000iu's per day, see here. Please also look through our page on Insulin Resistance, as this often occurs with PCOS. Take care Wray
Aug 27, 2013
 Progesterone cream
by: Anonymous

Yes, my doctor also told me to insert the progesterone cream directly into the vaginal with an applicator. 1/2 full, 2 grams for 3 times a week. It is the same applicator you use for yeast infection you buy in any drug store over the counter. I hope this help you.
Sep 24, 2013
 help with progest cream
by: lynsey

Hi, any help would be great.. im using the now progesterone cream, 20 mg a day for 2 weeks. libido came back almost immediatley but now cystic acne is breaking out worse and i am constantly sooo tired. I have been applying morning and night. thinking about doing just the nightime dose. My naturopath diagnosed me with low progesterone, i am also on a dim supplement along with angus castus and maca. I dont really want to higher the dosage as i feel its only going to make me more tired, what am i doing wrong?!
Sep 27, 2013
 help with progest cream
by: Wray

Hi Lynsey Using too little progesterone, it's only stimulating oestrogen. There's more info on our Oestrogen Dominance page. Agnus castus also has oestrogenic properties. One study found mild ovarian hyperstimulation syndrome occurred in the luteal phase, see here. Some have found maca affects them. It apparently has no affect on oestrogen or testosterone levels according to this one paper, see here. And yet this paper said it increased oestradiol levels, see here. It does appear to increase diastolic blood pressure slightly too, see here. These are two more papers here and here. We do have a page on Acne you could look through. And another on How to use progesterone cream. Take care Wray
Sep 27, 2013
 still struggling
by: Lynsey

Thanks for the quick response wray.. so what dosage of the cream should I be applying to you think? im quite a small girl.. about 110 pounds.. maybe less. So if i start having bad reactions just carry on with a high dose?
I actually have a few issues in all honesty im a bit of a mess!! ive had acne on and off for about 6 years. I seem to have different types, I have constant congestion, blocked pores, mainly on forhead and on cheeckbones and sides of face around hairline... never seem to go away no matter wot i use or dont use topically.. then i also get very deep painful cysts mainly on chin around mouth and jawline and neck. I went on spiro for about a year i looked and felt amazing, hair got thick, skin was clear.. and then i developed melasma on my upper lip.. i took myself straight off it... and acne now back along with the melasma, and i really want to correct this imbalance to cure these because im getting progressively more depressed as the weeks go by and im on this extreme healthy diet and not seeing the slightest change. I have never been on birth control, i would like to try it for my acne but now im scared that because i have melasma it could make it worse. I assume the spiro caused the melasma by highering my estrogen levels? any help would be great,pretty desperate at this point, very unhappy and not looking forward to anything because of my skin issues.

Sep 29, 2013
 still struggling
by: Wray

Hi Lynsey I've answered all these queries on your other page here. Take care Wray
Oct 06, 2013
 End of my rope
by: Anonymous

Hi, I have low progesterone and my period suddenly stopped 9 months ago. I got scans that ruled out pcos and despite taking the natural cream and acupuncture I got sik of the weight gain that I went on Yasmin. The side effects were so severe that I went off it after gaining 5kgs in 2 months...(note that I had cut out wheat, gluten, caffine, refined carbs, dairy, all sugar and exercise 7days a week). Even after stopping the pill and I'm back to square one....I cannot lose weight even eating the way I do and excercising and no period gain. I'm back on the natural progesterone cream 1/4 tsp twice daily and on vitex and getting acupuncture. Should I be putting some extra cream inside my vagina or am I using enough cream? When will I start seeing results in the weight department? It's really distressing me beyond words because I'm being so strict...and I'm only 27 HELP!!!
Oct 06, 2013
 End of my rope
by: Anonymous

Hi, I have low progesterone and my period suddenly stopped 9 months ago. I got scans that ruled out pcos and despite taking the natural cream and acupuncture I got sik of the weight gain that I went on Yasmin. The side effects were so severe that I went off it after gaining 5kgs in 2 months...(note that I had cut out wheat, gluten, caffine, refined carbs, dairy, all sugar and exercise 7days a week). Even after stopping the pill and I'm back to square one....I cannot lose weight even eating the way I do and excercising and no period gain. I'm back on the natural progesterone cream 1/4 tsp twice daily and on vitex and getting acupuncture. Should I be putting some extra cream inside my vagina or am I using enough cream? When will I start seeing results in the weight department? It's really distressing me beyond words because I'm being so strict...and I'm only 27 HELP!!!
Oct 09, 2013
 End of my rope
by: Wray

Hi there The weight gain was caused by using too little progesterone. I see you're back on the same low amount too. You're probably getting 20-40mg/day. A minimum of 100-200mg of cream should be applied. Too little progesterone stimulates oestrogen, which does cause weight gain. Oestrogen causes cells to proliferate, including fat cells, see here, here, here, here and here. Although a scan showed you don't have PCOS, you could still have it. Please scroll to the end of the page and see all the tests which should be done and ruled out before saying you don't have it. A scan just confirms there are no cysts on the ovaries. Please consider taking the nutrients listed on the page, many initiate ovulation and help regulate the cycle. Please have a vitamin D test done. Take care Wray
Oct 10, 2013
 confused
by: Lynsey

Im wondering why your dosage advice is so high wray?
are u saying that ppl should be on atleast 100mg of the natural cream.. im on now progesterone and on the tub it says 2 pumps a day which would give you 40mg.. 100 mg seems an awful lot, and its vry hard to rub in or put that much in your vagina.
Can you confirm that this is infact what your saying?
lynsey
Oct 10, 2013
 confused
by: Wray

Hi Lynsey I've answered all your questions before. But it's evident the cream you use does not absorb well. Some women use over 1000mg/day, see these comments here, here,here, here and here. Take care Wray
Dec 30, 2013
 Vaginal progesterone cream
by: Jules

I see that the best way to apply the cream is vaginally. Is there a specific over the counter brand to use? All the ones I have seen and used have not instructed you to use them in this way. I would rather not have to get it compounded. I agree with not getting enough on the typical 20-40 mg a day. I have been instructed to use this amount by several doctors over the years and it really hasn't helped with my severe insomnia. I would like to try vaginally and a higher dose on my own. Any advise would be appreciated.
Jan 02, 2014
 6 months post benzo :-)
by: Coralashley

Hello, it's been a long time since I posted. I do have a question.
But 1st an update:
I'm off the remeron (AD) and have been for over 40 days now :-) Praise the Lord! I'm on the Wilson's Temperature Syndrome t3 therapy and that is helping so much! I'm on 50mg progesterone pill and 30mg of progesterone cream, 1 x a day.

So here comes the question... my doctor sent me a urine kit to collect for my hormone levels. On the instructions it said to stop applying progesterone cream to your vagina, if you were doing so, and to apply it somewhere else on the body. So I did that and continued applying it away from the vagina for about a week..
During that week I've experienced less sleep, harder to fall sleep and some anxiety after 4pm and while I'm lying in bed, etc.
Do you think it's b.c I was having w/ds from me not putting the cream around my vagina?

Last night I went to go to bed at 10pm and layed in bed till after Midnight and then I thought wait the only thing I've done differently is I've changed where I put the progesterone cream.
So even though I had already put some on my inner arms, I went ahead and put some around my vagina area and took another progesteron pill and went to bed after 2am and then woke up at 6:30am.

You see last night when I was just lying there I felt very tired and wasn't thinking about anything, i was peaceful, but just couldn't fall sleep all the way.

Thanks for your insight! I've missed chatiing with you!
Hugs, Coralashley
Aug 10, 2014
 what cream does not use phenoxyentanol
by: Anonymous

I am curious about whether you know of any progesterone cream that is so natural it does not use Phenoxyethanol but does contain actual progesterone and not just wild yam. I notice that the companies that sell the natural progesterone products use this to keep it bacteria free and they say they use a small amount. They also use alcohol in their products and I am concerned this might cause irritation. I am post menopausal and after stopping the progesterone cream about 3 years ago, I have developed pretty severe atrophy and thinning of the lining, so much so that I occasionally get some light spotting. I am glad I just realized progesterone would help, but in the past I only used it topically and now I want to use it internally. Can you help with ideas about products that have none of the ingredients you are advising not to use. Thanks for the support and the great site.
Aug 11, 2014
 What cream does not contain Phenoxyentanol
by: Joy

You are quite right in not wanting to use Phenoxyentanol, it was banned for use in natural and organic skin care in June 2008, you might like to read the Skin Deep website. Natpro Progesterone Cream is 99.9% organic, you might like to read up on that. It is excellent when inserted in the vagina, but please do this at night as it does get messy. Also remember that progesterone needs to be used a minimum of twice a day as progesterone levels drop after 13 hours.

If you are going to try progesterone again, please read the page on Oestrogen Dominance.
Aug 11, 2014
 how to determine dose of natpro
by: Anonymous

Thanks Joy for the info about natpro. Looking forward to it coming back in stock soon. Any suggestions on how to determine amount to use in a dose if I'm wanting to start with recommended amount and then adjust based on symptoms? Sounds like I would want to use one dose internally at nite and the other during the day topically to get the 2 doses you suggested.
Aug 11, 2014
 recommendations for good labs to do saliva testing
by: Anonymous

Years ago I had a saliva test done at I think Aaron labs or something like that. Can anyone suggest a lab that does the kind of testing and gives the results suggested in the article I read on Wray's site. Sounds like there are good and not so good labs out there. Thanks for the support.
Aug 13, 2014
 Recommendations for good labs to do saliva testing
by: Joy

ZRT Labs USA, Genova Diagnostics UK and Genova Diagnostics USA.

Hope this helps.
Sep 04, 2014
 varicose veins?
by: Anonymous

Hi. I'd like to know if I try progesterone vaginally if it will have the same specific bad effect it has when i use it on my skin: varicose veins! whenever I apply progesterone to my skin, by the next morning i see the vein looks like it popped out and then stays that way. Since it has that effect on me, i'd like to know if its advisable - or not advisable - to try it vaginally. Of course I may not know if it gave me vericose veins there! Before anyone says "impossible", do your homework. While it was once thought that estrogen can cause varicose veins, its now been shown that the true culprit is progesterone. Thanks for info on vaginal vs skin for varicose vein problem.
Jun 10, 2015
 Progestron and period
by: Anonymous

How many days after using progestron vaginal we will see the period? I used 7 nights as my doctor told me , now after seven days finishing the last one, no period yet! Is it strainge or common? Should I wait more?
Jun 13, 2015
 Progesterone everyday during the month
by: Coralashley

Hi I take bioidentical progesterone only 50 mg pill at night and I take it everyday in the month.
I do still get my period, etc..
Is taking it everyday safe? Thank you!!! C
Feb 11, 2016
 progesterone dosage
by: Anonymous

All dosages you recommend are given in grams or ml could you please tell me what dosage to use measuring by teaspoon?
Feb 15, 2016
 Progesterone Dosage
by: Joy

You can read up on dosages on the How to use Progesterone Cream page.
Nov 23, 2016
 Garlic and progesterone cream
by: Cecilia

This might be the weirdest question, but.... I seem to have a vaginal infection. I always use a glove or garlic on a string for 3 days, then a tampon soaked in natural yoghurt with live culture. Within a week, I rid myself of the infection and I rarely get one.

Now, my predicament.... I just started with Vitex and progesterone cream due to perimenopausal symptoms. I put the cream in my vagina twice a day and fell AMAZING!! Would the garlic have any effect on my progesterone cream?!?

I love all your answers and find it extremely informative - thank you for helping all of us that would like to try and stay natural.
Nov 24, 2016
 Garlic and progesterone
by: Joy

Hi Cecilia

How interesting about the garlic, I have heard about yoghurt, but never garlic. Progesterone is excellent when inserted in the vagina at night, but do be careful with the cream used. Many contain ingredients that could cause more irritation. Natpro can be used safely, I use it every night.

Have you been tested for Candida by any chance, sounds to me like you could be suffering from it?

Candida

Also too much sugar in the diet could also be the cause of your infections.

Insulin resistance

Please consider stopping the vitex, it is estrogenic.

Take care.
Mar 11, 2017
 Application
by: Faith

Hello I hope this discussion is still active.

I am using bio-identical progesterone cream recently. I applied it to my skin as per leaflet instruction. Then I learned through this page that applying vaginally is more effective, so I started applying on the vagina lips and slightly inward.

Within two days I got my period which I thought was normal because my periods were getting shorter. So I stopped the cream and started again at day 12 applying vaginally. After two days I started my period again.

I understood that this was normal as it could indicate estrogen dominance so I kept my routine and increased my dose a bit.

The flow got heavier so it wasn't convenient to apply on my vagina anymore, so I started applying it on my skin again.

Within 2 days I felt the blood flow and pain reduced, so I switched again to vaginal application but then again it triggered more blood breakthroughs.

So I noticed it's a pattern that when I use the cream on my skin, blood and period pain almost go away, but when I apply it in my vagina area it's back within two days.

Is this normal and what shall I do? Shall I stick to applying on the skin?

Please note that I do annual pap smear and blood tests and all are OK. The last one was six month ago.

Kindly share with me your thoughts and your recommendations.

Thank you in advance.
Feb 06, 2018
 Progesterone and Estriol creams
by: Wondering

If you're using cream is it just as efficient putting it on a finger around outside of vagina and a little inwards or does it need to go into an applicator?

Also is it ok to use progesterone in vaginal area evenings and the oestrogen cream in the same area mornings or should they be put in different areas?
Feb 07, 2018
 Progesterone and Estriol cream
by: Joy

I use my finger, have done so for many years now. I can't really comment on the use of estrogen cream as I do not believe that any women should use it. The aim of progesterone therapy is to make progesterone the dominance hormone, by using estrogen you would have to use a lot of progesterone.

Please read these pages.

How to use Progesterone Cream

Estrogen Dominance

Environmental Toxins
Mar 02, 2018
 Dosage for men and rectum application
by: Anonymous

What should be the optimal dosage for a man with saliva progesterone result being 10 pg/mL?

And any idea, how to apply in the rectum as you cannot just put the cream on tip of the finger and insert it as it would be too less an amount and rectum muscles are more tighter than vaginal so how can a man get the best results from Progesterone cream?
Mar 05, 2018
 Dosage for men and rectum application
by: Joy

I would recommend that you start with 10mg progesterone per day, half in the morning and the other half at night. If you feel that amount is not helping then use more, you will have to experiment to see what suits you best. Between 10mg-100mg is recommended for men, more if symptoms are severe.

Progesterone for men

An applicator would be the thing to use if you are wanting to insert in your rectum. The 'finger' is really used by females when inserting in their vagina, or they can also use an applicator obtainable at pharmacies.
Aug 23, 2018
 Progesterone cream in vagina not causing dermal fatigue?
by: Melissa

Hi there, I’m trying to read the forem but it cuts off so I thought I’d try to write my own.

I started taking progesterone cream two cycles ago for pcos and really low progesterone levels. I’ve been rotating the application, taking 60mg per day of Dr Lee’s progesterall.

I read from Dr Mercola that the vagina is a better application place but I don’t understand why that won’t cause dermal fatigue as well?

Also, my estrogen dominance is getting worse. My mood swings were aweful the 1st month and a tiny bit better this month. My boobs have shrunk and my belly looks like I’m pregnant. For a pcos person I am fairly thin and I can’t fit into my jeans. I am eating only 1000-1200 calories just to try to maintain weight but it still won’t come off. I’m losing more hair too. It’s getting really frustrating. I’m also exhausted, but still can’t sleep at night with adrenal fatigue. I try to work out regularly but I’m really having a rough go. Is the 60 not enough? My doc says I should have never gained weight or bloated like I have so hasn’t raised the dose yet. This cycle is almost done before period so I don’t know if I should continue next month. I don’t think I can handle more weight and belly fat.

Let me know about the dermal fatigue or of you have any other help. Thanks!
Aug 24, 2018
 Progesterone cream in vagina not causing dermal fatigue?
by: Joy

Hi Melissa

You are not using enough progesterone. Between 100-200mg is needed, more if symptoms are severe. Weight gain can happen if not enough progesterone is being used. Using less than 100mg per day will aggravate estrogen receptors causing Estrogen Dominance symptoms to increase which is what is happening to you. Please read the How to use Progesterone Cream page. The cream should be used no less that twice a day, half in the morning and the other half at night. Use every day until your symptoms start to improve and the cycle is regular. Then use by following your cycle. It can take 2-6 months before things improve. The PCOS page may also help you.

Vitamin D3 is very important as a deficiency reduces the benefits of progesterone, optimal range is between 70-100ng/mL. Nothing less than 5,000iu's is needed daily. Co-factors are needed when taking D3, magnesium and vitamin K2 with no soy are the important ones.
Aug 24, 2018
 Build up
by: Melissa

Thank you so much for your prompt reply. I will finish this cycle out (only one day left of progesterone), and then up my dosage next month.

I read your application methods page but I am still a bit confused. I would like to put it in my vagina, but am concerned that continual use will cause dermal fatigue there as well. I couldn't find anything as to why it would our wouldn't do that.

Also, my Hormone Doc has me on the cream days 7-27 but I am not in perimeopause per my tests, only estrogen dominance (levels were 12 and 8 saliva testing and they told me that should be half that) and progesterone deficiency (levels were 4 instead of 80-110 saliva testing) I am concerned about the days 7-27 as I am worried about the cream building up and symptoms becoming worse.

I also have severe melasma (adreanal fatigue) and t3 thryroid elevation low iodine. I am 38, but have managed my pcos well up until the last year when I had two late cycles. (I don't usually have irregular ones or insulin resistance).

I'm taking a million supplements too but continue to feel worse along with the new hair loss and exhaustion.

Would you still recommend the progesterone for the 21 days at just the higher dose? Will estrogen dominance continue to get worse if I keep upping it and it's still not the right dose? My only current PCOS symptoms are the belly fat, facial hair and progesterone deficiency. Well and in the last 8 months hair loss.

I'm so tired and frustrated, I saw a nutritionist for two years before these guys and they couldn't help either.

Thanks again! your last response was helpful!
Apr 27, 2022
 Pmdd/low oestrogen
by: Anonymous

Hi when you say apply progesterone cream vaginally you mean inside? I’m using biovea cream so natural cream would I do this?

Also my issue is low oestrogen and I suffer with severe pmdd joint pain mood being the top issues.

I’m not sure what I should be talking to balance the hormones any suggestions on this would be appreciated

Thank you
Sarah
Apr 29, 2022
 Pmdd/low oestrogen
by: Joy

Hi Sarah

Correct, insert in the vagina at night. I can't speak for Biovea Cream, you will have to do your research to see if any of the ingredients will cause discomfort. It would not be progesterone, but rather the other ingredients that it contains that could cause discomfort. Natpro Progesterone Cream is excellent when inserted in the vagina. It is a 3% organic cream.

You are actually suffering from Estrogen Dominance. Biovea should have helped you with this. I am not sure how long you have been using it or how much you are using, but you might consider switching to Natpro.

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