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How long can you use progesterone cream for?

Hello,
I believe I am currently in the peri men0pausal phase in my life. Is it safe to use bio identical progesterone cream indefinitely? I was reading that it inevitably builds up in the tissue over time. If this is the case, can high levels become toxic and potentially cause problems?

Thank you,
Jessica

Comments for How long can you use progesterone cream for?

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Mar 25, 2024
 Progesterone Misconceptions
by: Joy

Hi Jessica

Oh dear there are so many Progesterone Misconceptions about progesterone, this would be one of them. Usually uninformed people/websites spread this misinformation. Also the word bio identical is just a fancy word used for natural progesterone.

If progesterone was toxic then every single pregnant woman would become toxic as the body produces huge amounts of progesterone while pregnant. As mentioned in a post before this. I am 68 and have been using Natpro for 20 years now, every day with no breaks and I will continue to do so. I certainly wouldn't be using it if it were not safe or if it caused a toxicity concern. Natpro progesterone cream has been my life saver.

Please read the How to use Progesterone Cream, Estrogen Dominance and Peri-Menopause pages should you decide to try it.

Take care.
Mar 25, 2024
 Antioxidants
by: Anonymous

Thank you, Joy!

Another question, perhaps related to misconceptions on the internet, is the use of antioxidants to reverse many of the issues related to estrogen dominance and other disease.

I strongly believe in this, however, just wanted your opinion on the use of too many antioxidants? Is there such a thing? I believe there is literature out there that states too many can be harmful if levels used are too high? I would not be surprised if these claims were false.
Mar 26, 2024
 Antioxidants
by: Joy

Hi Jessica

When you say too many antioxidants, how many are you referring to?  Antioxidants are extremely important. They are needed to help with inflammation. Take the amino acid Cysteine (NAC) and Taurine for example.  Cysteine burns fat and builds muscle. A powerful antioxidant and free radical scavenger, it boosts the immune system, energy and metabolism. A precursor to glutathione, itself a powerful detoxifier of the liver. Selenium, zinc and cysteine deficiency result in reduced levels of glutathione. An anti-aging amino, reduces age spots, also used in the treatment of rheumatoid arthritis, cancer, burns and wounds. Lowers homocysteine, strengthens skin, nails and hair, chelates heavy metals including mercury and lead, a hangover remedy. Breaks down mucus so used in bronchitis, emphysema, tuberculosis and cystic fibrosis.  Taurine is needed for the digestion of fats and controlling cholesterol levels, as it is an integral part of bile. Useful for hypoglycemia, oedema, high blood pressure, epilepsy, heart disorders (high concentrations are found in the heart), and have a protective and soothing effect on the brain. Essential for assisting magnesium, calcium, potassium and sodium to enter cells, a lack can cause a drop in potassium levels in the heart, may be the reason for muscle cramps, and not a lack of minerals. Associated with zinc metabolism, a shortage of both may lead to impaired vision. Helpful in alcoholism and diabetes. There are so many vital and important antioxidants.  

I can find no evidence however, that antioxidants help to eliminate estrogen, they definitely help in so many other health issues though. There appears to be a lot of hype about carrots helping with estrogen. According to Ray Peat "the carrot salad helps to support your body’s natural detoxification system. This raw carrot salad may help with estrogen metabolism and aid in the detox of toxins from your system. You may find that it helps balance your hormones and reduce symptoms of PMS". Personally I have tried the carrot salad, while good for you, found it made no difference at all. However, this could be because I have been using progesterone for so long now. Progesterone is definitely the dominant hormone in my case.
Mar 26, 2024
 Antioxidants
by: Anonymous

Thank you so much for this information!

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