breakthrough bleeding

by Claire

Age 38 - Started progesterone after having a period at the beginning of March (periods are not regular...typically along cycle with heavy bleeding at the beginning). Was applying cream for about 14 days and now have been breakthrough bleeding since March 19th. I was initially using too low a dose of progesterone cream so have been increasing from 100mg (split twice in a day) to 160mg the past two days, and since the bleeding has not decreased, I am attempting to do 200 mg starting today. Should the bleeding stop soon, or do I need to stop? Also I've been concerned I could somehow pass progesterone to my children, or husband with this much being applied to me. I don't want to interfere with their hormone inadvertently. Any help with be so greatly appreciated.

Thank You!

Comments for breakthrough bleeding

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Apr 02, 2024
Breakthrough Bleeding
by: Joy

Hi Claire

Unfortunately these are the symptoms that occur once Peri-Menopause sets in.  It can be a torrid time for most women but with the correct use of progesterone things become easier as you head towards Menopause.  The following heavy/continual bleeding and clots is most effective and has helped so many women who experience the same as you.  If 200mg works for you, then that is wonderful.  Progesterone should be used every day going forward unless you want to conceive. In which case a regular cycle is needed which  is difficult in peri-menopause.

Heavy/Continual Bleeding/Clotting Protocol
400-500mg Natpro Progesterone Cream per day
2000mg N-Acetyl-Cysteine (NAC) per day
2000mg Taurine per day
5000iu's Vitamin D3 per day
1000mg Bioflavanoids or Vitamin C per day

Every single living vertebra produces progesterone. There is no need to be concerned about your daughter or husband absorbing it provided it is natural. Please bear in mind that if using Natpro, progesterone absorbs into the skin in a matter of minutes. I can't advise on other brands which are often thick and difficult to absorb.

Please make sure that your Vitamin D3 is optimal at 70-100ng/ml. A deficiency reduces the benefits of progesterone. Cofactors are vital.

Apr 22, 2024
Bad period on progesterone crea
by: Liz


I’ve been on progesterone cream 200mg for about 2 months now. I I’m pretty certain I’m in perimenopause (38yrs old) and had breakthrough bleeding after the first 14days but now haven’t had any until about 3 weeks of no bleeding. I had extreme pms symptoms leading up to it and now I have a really intense period starting yesterday. Still doing 100mg morning and 100mg night…should I just keep going and once my progesterone levels balance out in the body it will get better? I can’t afford to increase dose too much more because I’m already having to buy cream twice a month. Thanks so much for any insight!

Apr 23, 2024
Bad period on progesterone cream
by: Joy

Hi Liz

You are correct you are in Peri-Menopause (PM). It usually starts with most women around 35, see PM link given below. It is also a time when hormones go crazy hence your PMS. Progesterone levels drop sharply while estrogen remains the same. It's a time when your monthly cycle will become extremely erratic, clots, heavy bleeding. The correct use of progesterone will help greatly. However, there is nothing that will help the body aging but progesterone therapy does help to get women through this time.

I understand your concern about costs and I feel that the 200mg that you are using will help greatly. A reminder that it takes between 2-6 months of the correct use before positive results are felt, longer if symptoms are severe. Please do not stop but you must be prepared for some strange things to take place as the body becomes progesterone dominant.

Please do not stop using the cream. It is important to use the cream everyday going forward as the cycle has become erratic and impossible to use during your luteal phase. Please read the How to use Progesterone Cream page. Also make sure that your vitamin D3 level is optimal, link given below.

All the best.

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