Will progesterone cream help me?
Man 57 on trt for 4 years (since July 2019).
Take 10 mg micronized DHEA and 10 mg micronized Pregnenelone every day.
Take 60 mg test enth. e6d.
Last year in March I suddenly got bad insomnia and anxiety, upped my pregnenolone dose to 50 mg a day and stopped DHEA. After 2 days I was sleeping like a rock, but after 6 months using 50 mg pregnenolone a day I got sleep issues again, not as bad as last time but usually woke up in the middle of the night unable to get back to sleep.
Lowered the pregnenolone dose to 10 mg a day and my sleep improved but not as good as before the last sleep issues started. Then this June I went on vacation on Cyprus and after 3 days there I slept like a rock! And it lasted for a couple of weeks after the vacation, but then my sleep issues returned. Why did I sleep like a baby when I was in Cyprus? Sun exposure?
Now I have had bad insomnia for a couple of weeks and I’m exhausted, checked my serum levels for 17OH-pregnenolone, 17OH-DHEA, Progesterone and 17OH-Progesterone. DHEA was mid-range but the other tests was undetectable.
So, the situation is that I have undetectable serum levels of 17OH-Pregnenelone and Progesterone…
I got compounded progesterone cream 1.7% (17 mg pr. gram) at the pharmacy.
Should I try applying half a gram (one gram) twice a day to my inner thighs and do that for a week to see if there are any improvement in well being and sleep?