I was put on bio identical estrogen and progesterone for depression and felt better on the estrogen but when put on the progesterone, which was cyclogest I felt suicidal very quickly and stopped taking it. I had to stop the estrogen as you cannot stay on it for three months without progesterone. I was surprised the cyclogest made me feel like this as I'd taken natpro before and felt ok. The gynaecologist said I was intolerant to progesterone and that was probably why I felt depressed. Does anyone have any comments or advice about this?