Too much progesterone

My saliva test showed my progesterone was 421, and my estrogens were all at normal levels. What can I do to lower my progesterone?

Comments for Too much progesterone

Click here to add your own comments

Nov 10, 2007
Too much progesterone
by: Wray

Hi there, you would have to supplement with oestrogen, not a route I would recommend. Unless you have adverse symptoms, it can only benefit you. Progesterone protects blood lipids from oxidation, prevents the conversion of cholesterol to cholesteryl ester, thus preventing the deposition on artery walls, protects the nervous system, prevents deep wrinkles from forming and much more.

I have put the ranges below in pmol/L, as you can see your progesterone level is NOT too high. In fact it's below the average level, if the test was performed during the luteal phase:
17-oestradiol Progesterone
Follicular 2.0 - 8.0 pmol/L 53 - 193 pmol/L
Midcycle 6.0 - 17.1 pmol/L 142 - 522 pmol/L
Luteal 5.5 - 13.2 pmol/L 259 - 979 pmol/L
Non-ovulating 3.00 - 12.0 pmol/L 50 - 325 pmol/L
Male values 2.80 - 8.80 pmol/L 24 - 104 pmol/L

Dec 30, 2008

I am 38 years old. I had 2 healthy pregnancies. After baby 1 I developed hypothyroidism and have been on medicine for 10 years now. My doctor had me at 112mg and brought me down to 100 a few months ago. I had a lot of stress the last 2 months and now I have gained weight. I am extremely tired at the end of the day and I have no libido left (I was very low to begin with). I am irritable and feel terrible.

I just went back to the doctor today and was told my thyroid was perfect but that my progesterone was .8. I had the blood work done on the 4th day of my cycle. She said it will be low but that I was really low. Now she wants me to try taking the hormone orally beginning on the 12th day after my cycle starts. She is giving me 100/day.

Is it possible that I need the higher dose of synthroid even though my levels appear good? I felt mush better at 112mg. She did increase me back up to 112 today.

I don't know what to do. I am otherwise a healthy female and do not want to start taking a lot of medication that is not necessary. Help!

Jan 02, 2009
To take or not to take progesterone
by: Wray

Hi Robin. Having a baby is very stressful, and is likened to running a marathon. On top of this progesterone levels drop sharply after birth, often causing post natal depression. Was this checked for, rather than looking at the thyroid? It could be that all you need is progesterone, have you tried it?

More importantly were the adrenals checked? These overworked organs are often overlooked, but the hormone cortisol they make is needed by the liver to convert the thyroid hormone T4 into T3. Cortisol is also needed to facilitate the entry into cells of the thyroid hormones. So it could be your adrenals need help and not your thyroid. Stress affects the adrenals above any other organ, it might be an idea to have it checked. Synthetic thyroid hormone is not a good option, there are natural alternatives, please take a look at the web sites below:

Take care Wray

Dec 03, 2010
post menapausal progesterone question

Hi, I am taking 100mg of micronized progesterone daily. I also use the Vivelle dot 0.0375 patch for my estrogen replacement. I also take 10mg of DHEA daily. I have been doing this for several years and FEEL GREAT!

2 years ago my progesterone level was 9.5. I just did my blood work again and now its 62. Is this a problem?

No one knows I am 66... I look much younger so if its the progesterone, I don't want to change (unless of course its dangerous).

Dec 10, 2010
post menapausal progesterone question
by: Wray

Hi there I'm pleased you feel great, but oral progesterone is not the best delivery system, as most of it gets destroyed in the gut and liver, see Progesterone application methods. I recommend 100-200mg/day progesterone, dependant on symptoms. But via a method which delivers all the progesterone, ie injections, suppositories/pessaries or creams. I don't believe any women needs more oestrogen, we have enough as it is. It's in our food, water, air and the skin care we use, particularly suncreens.
Please see the website Our Stolen Future for more info on endocrine disruptors. And for more info on oestrogen, please see our page on HRT. I would avoid the DHEA too, it can cause cysts and cancer, see here, and here. I would say it is the progesterone causing you to look younger, a study done on facial skin found a marked improvement, see here. Whereas oestrogen, in spite of what we've been told, had no beneficial affect at all, see here and here. Your level of progesterone is not very high, which is indicative of the oral delivery system. With topical progesterone levels rise far higher, in some cases to 100,000, see here. As you feel great, the ratio of your progesterone to oestrogen must be within range. It's the ratio which is the critical factor, not so much the levels. We've found to feel well the ratio should be 600:1 and over, see here. Progesterone is not dangerous, we make over 400mg/day in the third trimester of pregnancy. Take care Wray

Feb 26, 2015
too high of natural progesterone
by: AlaskaLadyie

I just got the results of a saliva hormone test and it shows my progesterone level at 3200 I understand this is a VERY high level... I have gained weight I can not loose and have nil libido. What is the solution to lowering my progesterone level..I am an active 60 year old and eat paleo and am post menopausal
thank you

Oct 25, 2018
by: Anonymous


Click here to add your own comments

Join in and write your own page! It's easy to do. How? Simply click here to return to Benefits of progesterone.

Share this page:
Find this page helpful? Please tell others. Here's how...

Would you prefer to share this page with others by linking to it?

  1. Click on the HTML link code below.
  2. Copy and paste it, adding a note of your own, into your blog, a Web page, forums, a blog comment, your Facebook account, or anywhere that someone would find this page valuable.

Search over 8,400 pages on this site...