Progesterone to shrink prostate

by Jos

I am 75y old with a 'grossly enlarged' prostate (BHP). My enlargement started over 10y ago. I took Duodart for 2+ years, it killed my sex life but no shrinking of the prostate. I stopped duodart and for the last 6 months take 1 tamlosin-400 every 2nd day. No retention, but frequent small pees, only once during the night. Urgency seems decreased too. I do some exersise now and my diet is not bad.
I researched many sites and found yours, and I am sure progesterone is my best option.
I cannot find ANY doctor in Australia who practises progesterone therapy, but found a naturopath who, after I explained and gave her articles, gave me a prescripiton. This was Mar 2015.
I applied the cream for about a month but was unsure about the dosage (I think I applied 10 mg/d), but felt uneasy without any guidance; after all this is a hormone!
I noticed no change apart from slightly fewer bathroom visits, but maybe that was wishfull thinking.
But several weeks later I noticed I lost quite a bit of body hair, legs and chest. I also suddenly gained weight from 75 to 80 KG (167 to178 lbs), without any change in diet!
As I had read feedback on your site saying that, if the dose is too low, estrogen dominance may first get stronger and one should increase the dose and perservere. Today I cannot find any post that mentions this.
Any suggestions please.
ALSO: do you know any Sydney/Aus practitioner with experience in progesterone therapy for men ?
Many thanks

Comments for Progesterone to shrink prostate

Click here to add your own comments

Apr 04, 2016
enlarged prostate
by: davidgmills

Just my anecdote. I had been told by my internist for a number of years that I had an enlarged prostate. He wanted me to see a urologist. I had been taking testosterone and switched over to progesterone. Very long story about how that occurred.

But after about six months of taking 60 mg of progesterone a day, I went to see a urologist. He told me that my prostate was normal sized and all tips to the urologist since shown that prostate is normal. I do have a spastic bladder of some kind and take medicine for it. I don't pee as well as I like but at least it is not my prostate causing this.

I really do believe I had prostate enlargement before I began taking progesterone because my annual prostate exams are not painful at all. They used to be very uncomfortable.

I have a friend who was having high PSAs of about 7. Three months on 60 mg of progesterone brought his PSA down to 1 and it has stayed there for a number of years and never gone back up.

You are not taking nearly enough progesterone to do yourself any good. 60 mg minimum. You could do 80 or 100. And adding pregnenolone of about 100 mg oral a day will keep your progesterone levels stable. I also take 25 mg a day of DHEA.

Sep 13, 2021
My experience
by: Anonymous

I too have been told since my 20s that I have a large prostate. I am now in my 80s. About 10yrs ago, I started having to get up to pee 2-3 times during the night and I also noticed that I was getting a mild pain in the perineum. I had prostate scans and PSA tests that were all 'normal' for my age.
Then I read on line that progesterone cream applied to the perineun had proven to be prostate protective because it keeps oestrogen away. It is thought that, as testosterone diminishes in older men, is is replaced by oestrogen, which can cause prostate cancer, in the same way that it is thought to cause ovarian cancer in older women.
I started researching the subject on authentic medical sites and found a lot of recommendations for progesterone cream.
So, I bought some progesterone cream and started applying 5mg per bedtime to the perineum. I was amazed to find that mild pain disappeared immediately and did not come back until
I stopped applying the cream.
I have regular PSA tests and the results continue to be very low.
Withut hesitation, I would recommend the use of progesterone cream or gel for older men, particularly those who have perineum discomfort or 'high normal' PSA readings.
Progesterone is thought to be a very safe hormone so is useful for those with mild symptoms. Any man with concerns about their prostate should, of course consult their family doctor or a urologist.

Click here to add your own comments

Join in and write your own page! It's easy to do. How? Simply click here to return to Progesterone faq.

Share this page:
Find this page helpful? Please tell others. Here's how...

Would you prefer to share this page with others by linking to it?

  1. Click on the HTML link code below.
  2. Copy and paste it, adding a note of your own, into your blog, a Web page, forums, a blog comment, your Facebook account, or anywhere that someone would find this page valuable.

Search over 8,400 pages on this site...