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progesterone has got rid of period pains but at a cost

by angie
(uk)

Hi wray,
after years of pmt, period pains, weight gain and mood swings i found your website and ordered progesterone cream. i began as initially instructed using 14 days from begining of ovulation (first 3 months) however i now use it every day (nearly 2 teaspoons for last 6 weeks) due to obvious symptoms of oestrogen dominance. i also had my vit D levels tested and now take a suppliment of 2000ug a day as my vit d levels were low.
however i seem to still have continual oestrogen dominence symptoms and am not sure what else to do. the financial cost of course at the moment is high i am willing to continue however i am now on my 6th tube with no apparent light at the end of the tunnel and im frightened it isnt working. i specifically struggle with my temper, water retention and hot flushes where it looks like ive literally dunked myself in a swimming pool this is increasingly embarrassing in social circumstances. i know the treatment can take time but what happens if i continue and it eventually becomes clear it isnt working???

any advice will be welcomed
Many thanks Angie

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Jan 05, 2012
 progesterone has got rid of period pains but at a cost
by: Wray

Hi Angie It can take time and sometimes large amounts to work. It's a pity about this, as it is costly. I'm happy the period pains have gone though, progesterone and it's metabolite allopregnanolone are potent analgesics. I have found 400mg/day is needed to stop hot flushes, which usually go quite quickly on that amount, as does the Oestrogen Dominance. You're currently using about 330mg/day. Interestingly a study done on hot flushes using 300mg/day oral progesterone took 12 weeks to reduce the flushes by 56%, see here. Although oral progesterone is not the best Delivery system. I'm happy to hear you had your vitamin D tested, and taking it too. But please increase the amount to 5000iu's per day minimum. Anything less won't raise blood levels high enough. You live in the UK where most people have very low levels, as there's insufficient sun to make vitamin D most of the year. The NHS's adequate level of 50nmol/L is far too low, it needs to be much higher. For more info on levels, testing etc see the Vitamin D Council, GrassrootsHealth, Birmingham Hospital and Vitamin D Links websites. Blood levels should be 175-250nmol/L and not the 50nmol/L most labs and doctors regard as adequate. The minimum daily dose should be 5000iu's per day, although the latest research indicates it should be 10,000iu's per day, see here. I've found that women who get their levels up high respond better, as a lack of vitamin D reduces the benefits of progesterone. A lack of serotonin is sometimes responsible for hot flushes too, we do have more info on how to raise levels by taking tryptophan. Please see our page on Natural Antidepressants. Continued below.
Jan 05, 2012
 progesterone has got rid of period pains but at a cost Part 2
by: Wray

Hi Angie You might like to see these comments here, here, here, here, here, here and here. from users of high amounts. Take care Wray
Jan 05, 2012
 thankyou x1
by: angie

hi Wray, thanks for your response the title of this is because im sure the thankyou will be one of many.
im awaiting vit d tablets that are 5000 so hopefully theyll help when they arrive and ive increased my progesterone cream doasage slightly to see if that helps any.

ive read the messages from other women who use high dosage. i suppose my fears are as theirs that this will be something i have to do for a long time but its good to see improvements for them. ill keep you updated hopefully this will help another reader in the future to keep going
many thanks Angie
Jan 12, 2012
 Vitamin D
by: Joy (South Africa)

Hi Angie - there is a lady in Kent who stocks vitamin D in 2 000iu's, 5 000iu's and 10 000iu's. I am sure that Wray will put you in contact with her. I am unable to post a link here, otherwise I would.
Take care.
Jan 17, 2012
 thankyou x1
by: Wray

Hi Angie I do hope you eventually come right, it isn't a quick fix for some. And I'm delighted you are getting a higher dose of vitamin D. And thanks to Joy who reminded me there is someone you could contact for the vitamin D, her details are here. Her name is Jo. Please consider having the test done, in fact every six month's is best, as levels drop with the seasons and stress. Please keep us updated, it's always good to know. Take care Wray

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