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Progesterone for simple hyperplasia

by Amy
(Delaware)

I went to the dr. and was diagnosed with amenorrhea after coming off of the pill for 8 years. I have not had a regular period in almost a year now which during that time I was TTC. After my hormone levels were checked (all normal) I had a biopsy where my dr. informed me I have simple hyperplasia. I am to begin taking 100mg progesterone for 14 days the first month, followed by 12 days the following 2 months.

I'm confused about if this will help me to ovulate? I haven't been ovulating since I haven't been having a menstrual cycle anyway. I know the progesterone will help to shed the build up of my uterine lining and cause a period...but is it possible that I could ovulate during this time? My dr stated that I should start to bleed 2-7 days after I complete the 14 days.

After these 3 months I will go for another biopsy and my dr. said we can look at going on chlomid to help start ovulating, but I'm not clear if taking progesterone alone could help me to ovulate? (as I feel that since all other hormone levels are fine, maybe progesterone will be enough?) I would prefer to not take chlomid so any help would be great, thanks!

Comments for Progesterone for simple hyperplasia

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Aug 27, 2011
 Progesterone for simple hyperplasia
by: Wray

Hi Amy All Contraceptives have the potential to cause adverse side effects, while taking them and after stopping. You might like to read these comments from one user of the pill, now using progesterone, see here and here. You mention 'taking' the progesterone, I'm assuming your doctor is giving you oral progesterone. This is the least effective Delivery system. Most of the progesterone gets destroyed by the gut and liver. Injections, suppositories and the creams are the most effective forms. As you don't have a cycle to follow, using progesterone for 14 days, with a 14 day break, as your doctor suggests, is a good plan. The natural cycle length will assert itself in time. For more info see our page on How to use progesterone cream. I recommend 100-200mg/day, more if symptoms are severe. I don't believe the 100mg he's suggested will be enough, and certainly not enough if oral. Although your cycle was damaged by the pill, and not by PCOS, you might like to read our page on PCOS, as this page explains how to use progesterone if anovulation is occurring. It also suggests antioxidants to take too, as often the damage is caused by oxidative stress, contraceptives cause this. A normal luteal phase is 12-14 days long. I prefer using the full 14 days, to ensure enough progesterone is used. If you have your test results, please check the ratio of progesterone to oestrogen, this is the critical factor, and not so much the levels. From Saliva Tests we run, we've found the ratio of progesterone to oestrogen should be 600:1 and over. Progesterone is essential for ovulation and normal ovarian function, but so is vitamin D, please have a test done. I'm running out of space so will start a new comment below. Take care Wray
Aug 27, 2011
 Progesterone for simple hyperplasia
by: Wray

Hi Amy Vitamin D low in most of us, see here, here, here and here. For more info see the Vitamin D Council, GrassrootsHealth and Birmingham Hospital websites. The minimum daily dose should be 5000iu's per day, and the blood level should be 70-100ng/ml, and not the 30ng/ml the labs and doctors use as a cut off point. Vitamin D is essential not only for ovulation, but for a successful pregnancy and vital for a growing foetus, see href="http://www.grassrootshealth.net/press/92-press-20100430" target="_blank">here, here, here and here. These are excellent videos to watch too, see here and here. We do have a page on Pregnancy, which explains the role progesterone plays, and how to use it. Finally please avoid clomid, see here, here and here. Take care Wray
Aug 29, 2011
 Thanks!
by: Anonymous

Thank you! I will look into all of that information. I will also look into the cream. I'm surprised my dr. did not mention it as I actually have trouble swallowing pills (even though they are little) and would have preferred a cream in the first place.
Aug 30, 2011
 Thanks!
by: Wray

Hi Amy Many doctors don't believe the cream works, this might explain it. I can assure you it does, as testified by the millions of women who use one. Plus you might like to see these papers which also show it does, see here, J Steroid Biochem Mol Biol. 2002 Apr;80(4-5):449-55 and and here. Take care Wray

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