Progesterone for PMDD and coming off contraception

by Claire
(Pennsylvania )

I came by the idea of bioidentical progesterone therapy while I was researching PMDD. I currently have a hormonal IUD (Kyleena). I plan to take it out in the middle of August and allow my body to heal naturally.

I have been using ProgesterAll (now discontinued) for my last two cycles. The first cycle, I started to use 20-40 mg/day the second day of my luteal phase, which was only one week long (days 20-26).

\My second cycle, and the one I just finished, I took his advice to “load” my progesterone intake. I tried 80 mg/day, felt too nauseated, and dropped down to 60 mg/day. I also took it one day before ovulation (days 18-26) because I felt like the 7 days weren’t enough.

I am now on what I’d usually think would be day 2 of my period, but I feel like my estrogen is already starting to pump. I assume that’s because the cream is starting to sensitize my estrogen receptors. Does this mean that I should continue upping my dose of progesterone next cycle? I am very interested in learning how to properly use it, particularly after my IUD gets taken out. I am also very interested in buying your brand after I’ve finished the last of my ProgesterAll.

Also, if I have a short luteal phase, should I start when it begins, or start where my ovulation “should” happen?

Thank you very much,

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Aug 02, 2022
Progesterone for PMDD and coming off contraception
by: Joy

Hi Claire

It appears that you have posted the same message on a few other posts which I have deleted.

I suggest that you start using progesterone as soon as possible as it will help support the body when you have the device removed. Unfortunately you were not using progesterone correctly. Between 100-200mg is needed. If you have a regular cycle, then use the cream by following it i.e. your luteal phase. As you don't know when you ovulate I suggest that you use the cream every day with NO breaks until your cycle reverts to normal, then use during your luteal phase. The luteal phase is always, no matter how long or short the cycle, the last 14 days before bleeding. The peak would always be ±7 days before bleeding. A defective luteal phase can be one that's too short, or the corpus luteum is not producing sufficient progesterone. Thus making estrogen the dominant hormone, progesterone should be dominant in the luteal phase.

It can take 2-6 months for the body to adjust to progesterone IF used correctly. The How to use Progesterone Cream page explains in more detail as well as using progesterone as a contraceptive. Don't waste the cream that you are using, just increase it so that it equates to that of Natpro which is a 3% cream. Once finished you can order Natpro if you wish. Just a note on using progesterone as a contraceptive. Stress and certain meds can disrupt things a little. It is advised to use extra precaution if experiencing this.

Please take note of Estrogen Dominance symptoms which you may experience while the body adjusts to progesterone. The aim is to make progesterone the dominant hormone at all times.

Please make sure that your Vitamin D3 is optimal as a deficiency reduces the benefits of progesterone. It is also connected to every single function cell in our bodies making it vital.

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