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Progesterone and Estradiol

by Lisa
(Alabama)

My Dr. recently put me on Estradiol for low hormone levels. My question is do I also need
to take Progestrone with the Estradiol? I've had a hysterectomy but I still have my ovaries.
Can anyone answer this question?

Thanks,
Lisa

Comments for Progesterone and Estradiol

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Nov 30, 2011
 You Need Progesterone
by: CamperKat

Yes, absolutely...estrogen therapy after hysterectomy must ALWAYS be balanced with progesterone. It is just mind-boggling that MDs still don't know this, even when it is literally their business.
Dec 02, 2011
 Progesterone and Estradiol
by: Wray

Hi Lisa If you are being given oestradiol, then as CamperKat says, you should be on progesterone too. But are your oestradiol levels low, as it's not the amount that should be checked but the ratio between progesterone and oestrogen. From Saliva Tests we run, we've found the ratio should be 600:1 and over to feel well. Please see our web page on HRT, to my mind it's not worth the risk. I've yet to find any benefits either. We do have more info on our Menopause page. Take care Wray
Feb 03, 2012
 Help please!!!
by: Anonymous

I had a partial hystorectomy 3 yrs ago. They removed my uterus and my right ovary, after ther birth of my 5 child. About 6 months later I fell into a dark depression having suisidal and homicidale thoughts. It was horrific. They tried anti depressants, that did not help. Well dec 6 2011 they removed the other ovary and started hrt. I have been on 0.5 of estridiol twice a day and I'm still having some issues. My dr. Has tried enjuvia but I had side effects. He said I am sensitive to hormones. Well the past few days my depression is back and night sweats. Should I be on pogesterone? Now I was diagnocted with pmdd, and thought after ther removal of my other ovary this would all stop, but for some reason I'm still having issues. Is there hope for me???
Feb 03, 2012
 Help please!!!
by: Wray

Hi there I'm not surprised you had adverse side effects from the Enjuvia, and that the anti-depressants didn't work. Removing the ovaries, removes our main source of progesterone, this is rarely thought about. I don't wonder you don't feel right. It seems to me you do need to replace the progesterone, but I don't advise oestrogen in any form, see our page on HRT for more info. I recommend 100-200mg/day progesterone, but I feel you'll need at least 200mg or more. If you do try it, please use sufficient. Too low an amount can worsens symptoms. But before you try it, please see our page on Oestrogen Dominance. Initially progesterone stimulates oestrogen, to overcome this it's essential to use enough. If you should experience it, please do not reduce the amount of progesterone, rather increase it. As you're now in surgical Menopause, and therefore have no cycle, it can be used daily. And of course there's hope for you, there's always hope! For encouragement, you might like to read these comments from users of high amounts, see here, here, here, here, here, here and here. Please have a vitamin D test, it's an essential nutrient, low in most of us. Progesterone is excellent for depression, but so is vitamin D, see here and here. Continued below.
Feb 03, 2012
 Help please!!! Part 2
by: Wray

Hi there For more info on vitamin D levels, testing etc see the Vitamin D Council, GrassrootsHealth, Birmingham Hospital and Vitamin D Links websites. Blood levels should be 70-100ng/ml or 175-250nmol/L and not the 30ng/ml or 75nmol/L most labs and doctors regard as adequate. The minimum daily dose should be 5000iu's per day, although the latest research indicates it should be 10,000iu's per day, see here. We do have a page on Anxiety, please read through it as it gives a list of natural anti-depressants. Take care Wray

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