by Joanne

Recently I was diagnosed with a genetic condition called Hemochromatosis. This genetic condition allows the body to absorb too much iron. It affects every organ system in the body including the endocrine system. The endocrine system suffers metabolic syndrome from too much iron. Metabolic syndrome is caused with an issue of insulin in this case when too much iron is deposited in the body. Nothing has ever been mentioned about estrogen and progesterone although they are part of the endocrine system also they as well as insulin are all hormones.

Is there anyone on this forum or in the know about hemochromatosis and can advise me about using progesterone? I have in the past used progesterone faithfully as advised from this site but never saw the results described by Wray. Could that have been because of the unknown genetic condition, hemochromatosis? In fact, my symptoms never abated or changed at all. When I found out I have the genetic condition hemochromatosis I was told at that time that it could affect the whole endocrine system as well as every other system in the body to one degree or another, but no one ever told me how to navigate these issues and find help.

Please, if you know about this condition, please advise me. Thanks!!


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Mar 08, 2021
Is there a connection between Hemochromatosis, progesterone, & estrogen
by: Justine

Hello Joanne,

Do you know what your Vitamin D levels are?
I have found a few papers on the link between Vitamin D deficiency and iron levels. Please take a read of these:

Low Serum 25-Hydroxyvitamin in Hereditary Hemochromatosis: Relation to Iron Status

Vitamin D deficiency, cardiac iron and cardiac function in thalassaemia major.

Taurine also seems to be beneficial in helping the body eliminate excess iron, please take a read of this paper:

Taurine supplementation reduces oxidative stress and improves cardiovascular function in an iron-overload murine model.

It may be a good idea to get your Vitamin D level tested and then supplement with Vitamin D and Taurine. Please read the papers first and consult with your medical practitioner and then you can make an informed decision.

We trust this helps and wish you all the best.

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