How Does Progesterone Finally Overcome Estrogen Dominance?
First I'd like to thank you for stepping outside the box to help yourself and others to find a better quality of life. I'm an RN and a natural health consultant. I get excited when I see others finding ways and methods of healing that have been overlooked or dismissed by the mainstream.
Natural progesterone therapy is a fairly new realm for me. I'm almost 49 years old and about 5 years ago started becoming aware of the very prevalent estrogen dominance issue on this planet. However, I did not really start looking into progesterone therapy until recently as my specialty is detoxification and digestive healing. As I step further into the world of hormones I see more and more how toxicity and digestive issues intricately wrapped around hormone issues.
I feel I have been estrogen dominant since the age of 15. Stressful childhood, drinking alcohol starting at around the age of 14 followed by more chaos as the years progressed. I finally cleaned up my act about 20 years ago and went on to open my own detoxification and digestive healing business.
I started using progesterone cream about 8 weeks ago using about 200mg per day. After a couple of days of continual headaches and nausea, things improved. Moods much better, deeper sleep, better skin. Up until I started using the cream I had a 28 day cycle. I chose to use the cream continuously as I didn't use the cream on the first day of the first period and got extremely agitated. By that night I was desparate and used it with much relief. I've since had one more period (24 days later) and used straight through and had a lighter shorter period with less PMS symptoms prior to its onset.
I retain a lot of water all month long, for years now, since my twenties but much more so in my forties, and other lab work has shown no serious conditions causing the water retention. I had two children in my late 30's and retained huge amounts of water, especially with the first pregancy. I've been diagnosed with adrenal exhaustion on and off per saliva testing by a naturally inclined MD, and I take about 2.5mg Cortef twice daily for 3-6 months at a time for about 10 years on and off during stressful times. I've currently been back on the Cortef since November. The progesterone really helps me to sustain a more even energy pattern. I haven't gained any weight while using the progesterone cream but haven't lost any water weight. I've been quite puffy for about 2 years now and will have wild weight swings from day to day of 1-3 pounds. Breasts will gain 2 inches from morning to noon. Crazy. I know it takes time, 3-6 months. 8 weeks later with no water weight loss is discouraging but I'll continue to hope. I take other supplements to support my system, blood sugar balancers neurotransmitter support, etc. Many are the same as what you recommend. I agree with your recommendations.
1) What is your stance on continuous use of progesterone cream at around 200mg per day possibly causing progesterone receptor sites to become desensitized?
2) I have some difficulty understanding how the dormant estrogen receptors sites that are activated by progesterone don't cause a perpetual state of estrogen dominance. At what point does the progesterone finally get a chance to become dominant? If the progesterone is continually activating the dormant sites, does at some point the level of progesterone get high enough that this stimulation of estrogen receptors no longer causes issue, or do the estrogen receptor sites finally ALL get turned on completing that process thus allowing progesterone to get a stronghold? In other words, how is the balance finally achieved where progesterone wins? ;)
Any insight into these matters would be most appreciated. Thanks again Wray. Much love and peace.