I am having some pesky hormonal breakouts along the jawline, neck and chin...I take it this is a sign of estrogen dominance??? Doctor is suggesting spironolactone. Not sure if this is the right thing for me (side effects are a concern), so I am holding off for now. I have been using topicals like Benzaclin, glycolic acid, etc., but they just aren't working on these resistant breakouts. I was wondering if natural progesterone cream could be applied topically on acne? THANK YOU FOR YOUR REPLY!