HELP....Severe Migraines

by Sharon
(Whitesboro, TX)

I started using progesterone cream a few months back for hot flashes and migraines. Now I have noticed that usually either 3 days in my menstruation cycle or toward the very end of my cycle I am getting a terrible migraine. I had stopped applying the progesterone cream during my cycle (for 1 week) in the past and I have been fine, but last month and now currently I am suffering with a migraine.

I normally use 200mg daily (100mg applies 2x a day - morning & evening). I applied 100mg yesterday because I just couldn’t get any relief from my headache (knowing it is hormonal), and within an hour I thought my head was going to explode. I was afraid to apply more without finding out if this is normal and if it could be due to being estrogen dominant.

If I could get some help on this, it would be greatly appreciated! I’m 46 and entering into Peri-menopause. I was also struggling with very heavy and long periods, but as of right now that subsided a couple of months ago. Now it’s occasional hot flashes during my period and severe migraines.

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Dec 27, 2018
HELP .... Severe Migraines
by: Joy

Hi Sharon

You are correct, there is a connection between Migraines and hormones. Progesterone is an excellent anti-inflammatory whereas estrogen is an inflammatory hormone. I suggest that you try rubbing some cream all over your neck, particularly under your ears and on your face. Vitamin D3 is another potent anti-inflammatory effective for migraines see here. A lack of vitamin D3 also reduces the benefits of progesterone. Nothing less than 5,000iu's per day is needed. Optimal range is between 70-100ng/ml. Magnesium and vitamin K2 with no soy are important co-factors needed when taking vitamin D3.

As you are in Peri-Menopause I suggest using the cream with no breaks at all. You may even have to increase the amount of cream used this will help with Hot Flashes. You will have to experiment with the amount to see what suits you. Once things have improved you can slowly reduce the amount of progesterone used remembering to never use less than 100mg per day but I do find that when in peri-menopause 200mg per day is needed. Please read the How to use Progesterone Cream and Estrogen Dominance pages.

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