Estrogen dominance and pcos

by Sherry

I have recently been diagnosed with PCOS. I also suspect I'm estrogen dominant .
The following is a list of my symptoms
Moodiness and irritability
VERT sore breasts premenstrualy
Weight gain on hips and thighs
Bad migraines premenstrualy
Hot flashes at times

My question is this. I've been reading different sites and they suggest taking 40mg of the cream daily and this site is recommending 100-200mg. Why do you recommend such a high amount? I'm so worried things will get worse with that high amount due to the estrogen waking up.

Secondly, I've read about doing a suppression cycle where I would take the cream from days 7 till my period to suppress ovulation and give my body a break . Do you agree this is ok?

Thirdly, am I going to gain weight with this ? Iam already gaining weight and I don't want to gain more.

4. If this estrogen wake up happens how long till it goes away ?

Comments for Estrogen dominance and pcos

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Sep 09, 2013
Estrogen dominance and pcos
by: Wray

Hi Sherry Oestrogen is invariably dominant if a woman has PCOS. Anovulatory cycles are common, if not the norm. Testosterone is often high too. I recommend high amounts of progesterone as low amounts don't work for severe problems. 40mg/ml is the amount many women make during their luteal phase, if this did help, we would have no adverse symptoms. But when something is awry it won't. Besides which 40mg/day won't raise progesterone levels to those found in the luteal phase. Only sub-luteal levels are achieved, see here. A great deal of progesterone is needed to suppress excess oestrogen and testosterone. Progesterone alone won't help PCOS which is caused by oxidative stress, large doses of antioxidants are also needed to reverse it. There's a list of these on the PCOS link I've given you. I would always recommend using progesterone for 3-6 months on a daily basis to suppress the excess oestrogen, testosterone, FSH and LH. And to give the ovaries a rest. It's not so much to suppress ovulation which it will do, but to stop the cysts forming. High LH is causing the cysts, plus increasing testosterone levels. You will gain weight if you use too little progesterone, as it will be continually stimulating testosterone and oestrogen production. High amounts of progesterone lessen the Oestrogen Dominance symptoms, some women don't experience them. Please have a vitamin D test done, this is usually low in PCOS. A lack of it reduces the benefits of progesterone. Take care Wray

Sep 09, 2013
by: Sherry

Hi there
Thanks for all the info. When you say take it daily do you actually mean daily with no break for 3 to 6 months? Won't that stop my period from coming at all ? Or should I go on until my period then go off ? I'm so d ared to go on that high a dosage are you absolutely positive this is what I should do ? My estrogen dominance symptoms during the second half if my cycle are already unbearable and I'm scared if making it worse and I absolutely cannot gain anymore weight . Some sites I've read suggest taking a very low dose of 4mg. Day from cycle day 1 till 7 then increase to 8 mg a day from 7 to 15 then go to 20 to 40 for the remainder of the cycle . They said that will help reduce the estrogen wake up crisis . I'm just confused as to what to believe and to do

Sep 11, 2013
by: Wray

Hi Sherry Yes I do mean every day, through any bleeding too. 400mg/day and more are needed to stop any bleeding. This is the amount I recommend to women who have continual heavy bleeding. I'm not forcing you to chose my route, it's just that I know it works. So if it makes you scared you can try the one you've outlined above. My guess it will take years to come right. You might like to read these comments from users of high amounts here, here, here and here. It is essential to get your vitamin D level up, it's almost pointless using progesterone unless you do. And you do need to take those high doses of antioxidants too, progesterone alone is not going to help much. I see I forgot to give you some other pages we have. One on Migraines, which generally need 400mg/day. Another on Breast Tenderness which can be caused by a lack of iodine. And another on Hot Flushes which does need 400mg/day. Take care Wray

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