I have tried progesterone in the passed but increased my pcos symptoms (hair growth ect) I was using 200-400 so it makes so sense to me. I got off the cream the hair growth has reduced but am no experiencing sever anxiety, which I believe my cortisol has spiked trying to make up from the dose I had before. my question is if I start the progesterone again will it work because the progesterone receptors are being occupied and blocked by the higih affects of cortisol. Should I take it in combination with melatonin, or cortisol blocking agents? And if its my adrenals that are causig the problem, should dhea be taken with progesterone? and at what dose? do high/low cortisol play a factor?