5-Alpha Reductase

by Simon
(Brockton, MA,USA)

I have been taking finasteride for years for BPH and to keep my DHT under control.
In your website you say "research has found that progesterone is a natural inhibitor of 5-alpha reductase." Can you please cite your source for this information, in particular any reports from studies that support this statement?

Comments for 5-Alpha Reductase

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Aug 30, 2021
5-Alpha Reductase
by: Justine

Hello Simon, thank you for writing in.

I will provide a few links below, you will also find more on our website by typing in your search term in the customised google search bar found at the top of each progesterone therapy site page.

In particular you may like to read this forum page Please see the responses written by Wray, she gives quite a few research reports within her thread.

Further links:
In vitro study of rat prostate 5α-reductase activity and its inhibition

Effects of estradiol and an aromatase inhibitor on progesterone production in human cultured luteal cells

Progesterone receptor inhibits aromatase and inflammatory response pathways in breast cancer cells via ligand-dependent and ligand-independent mechanisms

Finasteride, a 5!-Reductase Inhibitor, Blocks the
Anticonvulsant Activity of Progesterone in Mice


In vitro study of rat prostate 5α-reductase activity and its inhibition

Warm wishes,
Justine

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