Why not Pregnenolone

by to

If Pregnenolone is the precursor to testosterone, progesterone, cortisol, estrogen, etc.... why not take that instead of Progesterone? Thx

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Jun 14, 2019
Why not Pregnenolone
by: Joy

Hi to

I see no point in pregnenolone, as it has to be converted into progesterone, but it is converted into DHEA too, which no woman needs more of. See here and here. The Steroidogenic Pathways explains in detail.

Jun 14, 2019
by: To

Thank you for your reply. I'm a man, so same thoughts? Is there more of a chance of DHEA turning into estrogen?

Jun 21, 2019
Pregnenalone Not Needed
by: Susan in Oakville

When adrenal fatigue is present, and cortisol is low in the body...supplemental Pregnenalone will convert to cortisol production NOT progesterone in the body. So you would end up with no improvement in progesterone levels. This is called the pregnenalone steal!

Dec 03, 2020
Preglenelone steal
by: Stef

This is what’s happening to me I believe! I have adrenal fatigue and lots of estrogen dominance. I feel a anxious while on 200mg cream. I am afraid to up my dose to find relief because I’m afraid it will make more cortisol. What do I do should I stop progesteone. I know I’m low I’m progestrone and also have high estrone levels and will benefit from the cream but I’m having anxiety and also insomnia at times on it! I’m desperate for any help thank you!

Mar 08, 2021
Pregnenolone steal
by: Anonymous

Hey I have the same issue right now lol I have low progesterone and I been taking 100mg for 3 days and have had insomnia and jitteriness at night I’m wondering if I should maybe wait a few weeks or so and try a much higher dose did u ever find a solution to ur problem?

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