Unbalanced the other way

by Kate


I wonder if you can help. I am oerimrnopausal, 45 years old. I was taking progesterone cream, as recommended, but I was suffering from higher estrogen levels as I tried to add more progesterone. My high estrogen was confirmed on a blood test at around 2000 pmol. Before adding progesterone it was 335 pmol.

I then added in a herbal mix - dim and sulforaphane, plus herbs to assist methylation at phase 2. 6 weeks later and I just had a Dutch test. My E is now very very low, almost postmenopausal. My Progesterone is within range at 54 nmol.

Now however, I am getting excruciating stomach pain if I use any progestetone cream at all. I have had to stop. I have also now stopped the detox herbs.

So I have now taken my estrogen too low.

My questions are:

Is my estrogen likely to rise back quite quickly?

Why am I getting excruciating stomach pain from prog cream when my estrogen is very low??? I thought women used progestetone cream after menopause when estrogen is very low. Right now I cannot take any cream. The pain subsides when I stop.

Be interested to hear your views on what I should go next???

Comments for Unbalanced the other way

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Dec 11, 2022
Unbalanced the other way
by: Joy

Hi Kate

Your post sounds familiar to me, perhaps I am mistaken. Anyhow, I am a little confused, you state a high estrogen level and give the result, then you ask a question about why you are getting stomach pain when your estrogen is low? Your test states that it is slightly on the high side. Please clear that up.

While each individual hormone test is important, it is the ratio between progesterone:estrogen that is important. You don't give your progesterone result. If you have your test results you can work out the ratio see here. The ratio should be around 600:1. More importantly, how are you feeling apart from your stomach pain?

Progesterone itself doesn't cause stomach upsets. Initially progesterone stimulates estrogen, the body needs to adjust to progesterone therapy. This can take between 2-6 months, longer if symptoms are severe. That is the only thing that I can think of that could be causing an upset, or It could be that an ingredient in the cream that you are using causing an upset. Have you looked into that? There is actually no evidence that progesterone causes stomach pain so something else is going on. Something is aggravating your gut or an ingredient upset. What cream are you using and how much? It is so important to know how much progesterone is being used. Information on this website is based on a 3% cream. Did you try rubbing progesterone cream on your stomach? As mentioned many times on this website, progesterone is an excellent anti-inflammatory.

I am not sure where you got that progesterone should be used after menopause. It is vital for every living vertebra, young and old, male and female.

You don't want estrogen to be the dominant hormone, progesterone must be the dominant hormone at all times.

As you have stopped using everything, including herbs, may I suggest that you start introducing them one by one. That will be the only way to find out what is causing the upset. Start with progesterone and see how you get on. If not using Natpro, and the upset starts up again, look into the other ingredients in the cream. Keep going until you find the culprit. lol

Good luck.

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