TTC and Just Want to Be Sure

by Marie

I am 44 years old. We are trying to conceive, and I just want to make sure I am not messing things up. My cycles are usually 26-27 days. I ovulate on day 13 or 14, and my luteal phase is 13-14 days long. By the looks of my chart, everything is fine. But I have had several miscarriages: two in 2014, then a baby in 2015 at age 42, and two more miscarriages in 2016. I have not conceived in a year, despite regular periods.

I had blood work done in January and my FSH was 7, confirming I was not peri-menopausal. My progesterone was 1.6 on CD 10 (which seems normal). My vit D was a little low, so I've been taking D since Jan, and making sure I get out in the sun. Also, my iron was low, so I've been on iron too. I take a multi-vitamin every day, as well as extra C (with my iron), cod liver oil, and sometimes alfalfa and spirulina.

I recently purchased a natural progesterone cream. It's a 25 mg dose pump cream. I am so afraid of using it. The instructions say to begin on CD 12 and end on day 27. I keep reading so much conflicting info. I know many who are using 100mg every day.

What do I do? According to the questionnaire, I strongly needed progesterone (score of 33), but I'm afraid of messing up my regular cycles. I read the pregnancy section on here, but it mainly speaks to those with a luteal phase defect...which I do not have. Yet, I DO have mood swings, some hot flashes, and fatigue off and on.

Can someone help me? I'm inclined to use a large dose in hopes of conceiving.

Any advice is appreciated. Thanks!

Comments for TTC and Just Want to Be Sure

Click here to add your own comments

Sep 19, 2017
TTC and just want to be sure
by: Joy

Hi Marie

I am so sorry to hear about your miscarriages which are usually caused by low progesterone levels and stress. Other factors can also have a negative effect. Your age alone indicates that you most certainly are in Peri-Menopause which starts at around 35 when progesterone levels start to drop causing hormones to go crazy.

While each hormone test is important, it is the ratio between progesterone and estrogen that is important. If you have your estrogen (E2) result, perhaps you can work that out if you read the Hormone Testing page.

I am afraid that you will mess things up if you are planning on using progesterone at that low amount. Nothing less than 100mg per day is needed, often more is needed. It all depends on how severe symptoms are. Not knowing what progesterone concentration is in the cream that you have makes it difficult, but it should equate to Natpro's 3.33% concentration which is organic.

If your cycles are regular, then use by following your cycle. In other words, the cream should only be used from ovulation, for the last 14 days of the cycle. Normally, when first using progesterone, one should use the cream every day for 2-6 months or until the body has adjusted. Once your monthly cycle returns to normal, then and only then must progesterone be used by following your cycle. In most cases monthly periods are messed up, but they soon assert themselves once the body has adjusted. Should pregnancy be confirmed, it is vital to stay on progesterone for the first 3 months at least. Please read the Pregnancy and Miscarriage pages listed below.

Low Vitamin D3 will impact greatly. I suggest taking 10,000iu's for 3-4 months, then drop down to 5,000iu's per day. A deficiency reduces the benefits of progesterone and is connected to every single cell in our bodies making it vital. It is so important for the mother and the unborn child. Co-factors are needed especially Magnesium and Vitamin K2 with NO soy.

Please read the following pages and the study references papers as they will help you.

How to use Progesterone Cream -

Estrogen Dominance -

Peri-Menopause -

Menopause –

Vitamin D3 -

Magnesium -

Miscarriages -

Stress -

Miscarriages -

Hormone Testing -

Sep 23, 2017
Re: Just Want to Be Sure
by: Marie

Wow, thank you, Joy for taking the time to answer me in depth. I look forward to reading those pages I have not yet read. I will wait for ovulation and then use 100 mg as you've recommended. I will also increase my D3.

My E2 was 99 in the follicular phase (CD10). My FSH was 7, and my progesterone was 1.6. I will take a look at the testing page as you mentioned.

Thank you again. This has been extremely helpful!

Click here to add your own comments

Join in and write your own page! It's easy to do. How? Simply click here to return to Progesterone faq.

Share this page:
Find this page helpful? Please tell others. Here's how...

Would you prefer to share this page with others by linking to it?

  1. Click on the HTML link code below.
  2. Copy and paste it, adding a note of your own, into your blog, a Web page, forums, a blog comment, your Facebook account, or anywhere that someone would find this page valuable.

Search over 8,400 pages on this site...