Troche versus cream

by Anna

Hi Wray,
Thank you for your great site! Very helpful!
I have been struggling with my health since I was 29 and I'm now 43. At 29 I ended up with a depression that was caused by candida and a huge amount of mercury in my mouth. I got it all sorted with diets, supplements and dentists and felt good again. At 34 I had my first child, I had 2 miscarriages in between and had my second child when I was 37. After about 3 months I felt this huge depression coming back. It felt even worse than my first one. All the doctors want to give me was anti depressants, I tried for a week but they made me throw up really badly so I refused to take them. I went to an integrated doctor who told me I was extremely low on B6. Again I got better after a few months and I was fine until 3 years ago when I hit 40. We live in Australia now and I went to another integrated doctor here. She did all these tests and I was lacking B12,Zinc, B6, my thyroid was low and my progesterone/estrogen levels were extremely out of balance. So for that she prescribed me progesterone cream and it helped a lot. I have noticed the last 3 years that I start feeling worse when winter hits. So she suggested me to take a troche at night instead of cream because that would be better. I've been taking it now for 3 months and I feel very anxious, have a lot of pain in one of my breasts and just don't feel good. So I asked the compounding pharmacy if it was natural what I was taking and they told me it's not. I'm so confused. Because all I've been through I'm so aware of what I eat, drink, sugar, gluten, vaccinations, antibiotics etc. and now I've been taking something that is probably not good for me at all while I thought they had prescribed me something natural. I come to realise now that these troches are not good at all. Should I gradually stop taking them or can I stop all at once and continue with your cream? I would love to try it. Thanks Anna.

Comments for Troche versus cream

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Jul 15, 2015
troche vs cream
by: jo

Hi Anna,
I too, am from Australia and have been taking progesterone in Troche form BioIdentical Hormones and Dim in capsule form. The progesterone is Half a 250mg troche @ night from Day 12 to 20 and then twice a day from Day 20 - 28. Dim Capsule the same way and I feel fantastic. Did your Doctor tell you whether the troches you are having are bio identical or not. I suffered from Severe anxiety as well, not anymore. I am a patient of the AMC ( Australian Menopause Centre) based in your hometown of Sydney. They have been fantastic. Maybe try them for some advice. They did hormone blood tests before they prescribe medication so they know exactly what you need based on Blood tests. They saved my sanity.

Jul 20, 2015
May I offer a suggestion?
by: Shalny

I don't have an answer to your question about how to transition from troche to cream although I think its a good idea that you do it and I'm sure someone will get back to you on the specifics. I did happen to notice that you didn't mention anything about vit D. It is very important to have proper levels in order for the progesterone to be effective. I'm surprised your integrative practitioner hasn't tested for it especially since things get worse in the winter for you. Click on the link on the left that says "progesterone and vitamin D". It will give you lots of good info while you wait for your response. Good Luck!!

Jul 23, 2015
Troche versus cream
by: Joy

Hi Anna

I am sure that Wray will appreciate you kind words about the website.

Any form of oral progesterone is not the best delivery method as 96% gets destroyed by the gut and liver, see here, and for troches, lozenges and drops, 50% gets destroyed by the gut and liver. Had your integrated doctor read the study papers, she would have realised this. She still beats the other doctor prescribing antidepressants though, so one up on her. Using the troche would have merely aggravated your estrogen receptors causing Estrogen Dominance.

Even though you suffered from depression from the age of 29, it can rear it's ugly head at Peri-Menopause which is where you are now. It is a difficult time for most women, but it need not be. Progesterone cream helps one through this and prepares one for Menopause. Please read How to use Progesterone Cream.

Do you know what your Vitamin D3 level is as a deficiency reduces the benefits of progesterone, it also helps with depression so too does magnesium, an important co-factor for vitamin D3.

Hope this helps you.

Jul 28, 2015
Thank you
by: Anna

Thank you ladies for all your very helpful comments!
I'll get everything checked that all of you mentioned and I have already swapped the troche for the cream.


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