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Swollen ankles

by Anna
(Texas)

Hi wray blessings to you and natpro i love this creme. I have been using progesterone for 7 years now I am 50 years old I use to use life flo then 3 years ago switched to natpro about 200mgs a day.
Anyway I love what natpro does for me energy mood etc but Ive noticed one problem that when I travel by air or car long distance my ankles and lower legs swell horribly. This year I took a trip to England but stopped the creme a few weeks before leaving and had no problems with swelling. On returning I resumed the creme and took a trip to California my legs swelled again. I understand that
Estrogen causes ankle swelling and that pg wakes the receptors but I have never in the 7years of using pg had estrogen dominace symptoms. I realize that stopping the creme then starting again can cause problems but after 7 years of using pg I dot understand why this would happen then not happen when I don't particulary have any other symptoms of Ed
Thank you in advance for ay insight love anna

Comments for Swollen ankles

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Nov 02, 2012
 Swollen legs
by: Karenina

Hi Anna,

It may well be that stopping the cream caused the swelling of the legs however when I had the same problem I found taking one teaspoon of Turmeric together with a quarter teaspoon of Cayenne powder a day reduced the swelling completely...it is a symptom of high blood pressure. With the progesterone cream it worked very well for me. Hope this is helpful to you. Take care. Karenina
Nov 03, 2012
 Swollen ankles
by: Wray

Hi Anna I'm delighted the progesterone has helped you , and that you love the Natpro. You are right, oestrogen can cause swollen feet, ankles and calves. So can flying and sitting for long periods without moving. I'm completed baffled why you get the swelling when using progesterone and not when off it. Cells swell when stressed, they become more alkaline, so retain water and loose sodium. Loss of sodium causes aldosterone to increase, which helps to retain it, but aldosterone also causes water to enter the cells, so swelling them further. Plus more magnesium and potassium are lost. Progesterone inhibits aldosterone and prevents the loss of sodium. Plus of course it inhibits oestrogen..... "Mitogens and carcinogens, including estrogen, cause cells to become alkaline and to swell......" You might like to read through this paper here as it explains oedema. He advocates the use of progesterone, salt too. But I can't find a clue as to why you get this problem, maybe you can by looking through it. Knowing what you eat or drink might present a clue too. I find this very frustrating, as normally I can find an answer by looking at the patterns. If you do find an explanation, I would so appreciate hearing about it. Love to you too, take care Wray
Nov 03, 2012
 Swollen legs
by: Wray

Hi Karenina Always happy to see your input! I'm so baffled by Anna's symptom, as it's not at all what I would expect. I'd forgotten about your turmeric/cayenne mixture, I hope Anna tries this next time she travels. Take care Wray
May 07, 2014
 Edema with Natural Progesterone too!
by: staceyd

I too have suffered swollen ankles with the natural progesterone. This seems like it is the OPPOSITE effect of what should be happening. One clue to my problem may be revealed in the sea salt and warm water flush that I will occasionally do. The first time I did it last year while doing the 10 day lemon/cayenne/maple syrup detox fast, I noticed that following the directions of 2tsp. of natural sea salt to 1 liter of warm water had NO EFFECT on me. I gradually went up every day and finally got results but that was at almost 5tsp of the natural sea salt to the 1 liter of warm water. Prior to menopause I suffered alot of neuroendocrine problems that were diagnosed as being DIRECTLY related to "estrogen dominance" caused by my sensitivity to xenoestrogens. I actually suffered from "seizures of unknown causes" for years before they were properly diagnosed and CURED by a premier neuroendocrinologist via 800mg/day of natural progesterone (made by compounding pharmacy)during the last half of my menstral cycle. All symptoms subsided within 3 mos of starting the natural progesterone. Since menopause, most of my symptoms have diminished or completely remitted (no longer have any seizures), but still experience issues (low thyroid & low adrenal) with xenoestrogens. Just recently started back on the nat. progesterone (over the counter cream this time - Progest cream) and have noticed the swelling of my ankles since 2 days after starting.
Mar 23, 2016
 swollen for 4 years
by: Anonymous

I have had incredible edema in legs since starting Nat progesterone. I also was diagnosed with Graves Disease and told swelling was from that. However, the thyroid was removed and I'm still swelling. I've tried going off progesterone on 2 occassions and swelling gets worse. And terrible emotion, depression and weight sets in.
Mar 11, 2017
 Swelling from compounded natural progesterone capsules
by: Anonymous

I decided to try going off the progesterone capsules because I've been on them for several years and I'm 61 and I wanted to see if they were helping me sleep or if I would notice any difference. And what I did notice is that my ankles have stopped swelling over the past few months. I just realized it's over the same amount of time that I stopped taking the capsules. I have been taking a low-dose diuretic for a few years now. I also used to have a lot of chronic nausea, and haven't had as much of that in quite a while either. Especially in the evening and now I'm wondering if it was also caused by the progesterone. I was on estrogen and testosterone cream but I went off it last year also. The only thing now that I use is an estrogen vaginal cream (estrace) once or twice a week. I also have migraines and I believe they have diminished somewhat. I don't notice any symptoms of menopause now or withdrawal from the hormones. I just put all this together and it helped me to find this site and other women's experiences.

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