Hi, I was just tested (saliva) for hormones, after feeling crazy for a few months, getting migraines, having 2 periods a month, weight gain, aches, insomnia, night sweats etc. My progesterone was a 12, my estrogen 1.99, and testosterone 64.40. SO, the doc prescribed my 30 mg of natural progesterone cream from the compounding pharmacy to apply at night, 2 hours before bed. The first night was fine, the next night was too. On the next morning, I woke up completely drunk. I couldn't function til around noon. I have panic disorder, so I never drink. SO, this feeling was very upsetting to me, and I hated it. The pharm told me the dose was too high, to cut it in half. I was scared to even take it again, so I cut it in half, twice. So Im taking 7.5 mg for 2 nights now. I feel fine, just a lil spacey at times- but I also take a VERY small dose of Xanax almost daily, that I have been trying to stop. Wondering if it will hurt me to slowly increase my dose of progesterone, because I cant take the risk of feeling like I did on the drunk morning. I have to drive for work daily.. BTW, I am extremely sensitive to meds. always have to take tiny doses of things.