Right dosage

by Claudia
(Chicago )


I followed your directions and took 200mg/day of progesterone. After almost 2 months on this dose I’m still in the stimulation mode. Going up to 400mg hasn’t given me the results I was looking for. It kept me up at night with no sleep at all. If I take 200mg in the morning I’m a complete zombie during the day. If I take that amount at night I won’t sleep almost at all. It's definitely not a refreshing sleep.

Honestly,I have reasons to believe (I have nipple hair since I was 11-13) that my imbalance started when I entered puberty (I’m 38 now). All these years I stayed away from birth control pills, but had such a miserable life (fluctuations in weight, puffiness, bloating,cravings for sugar that would make me homicidal, extreme fatigue, insomnia since age 17, joint pain since age 16, water retention, sore breasts, heavy menstruation, lots of blood clots).

I'm kinda afraid to go even higher than 400mg as I don’t know what dose I should stop at. I wanna be productive when I’m awake and have a restful sleep at night.

Can you please guide me? What amount to try next and how it’s best taken for maxim results?
Thank you very much!

Kind regards,

Comments for Right dosage

Click here to add your own comments

Jan 02, 2019
Right Dosage
by: Joy

Hi Claudia

It can be difficult to find the correct dose as we are all different, some women require more progesterone while others don't. You will have to experiment to see what suits you. You do need to give it time though, it can take 2-6 months. I suggest that you try to persevere with the 400mg per day while the body adjusts, I do not believe that you need to use more than this, but as mentioned, we are all different. Use the cream morning and at night, never use less than once a day. Try using the cream late afternoon if you are having problems with it at night, again experiment to see what suits you.

You clearly are suffering from Estrogen Dominance. Have you been tested for Insulin Resistance? You will notice that many of the symptoms are the same as estrogen dominance.

Heavy bleeding/clots does require 400mg until things improve. Try the following protocol.

* 400-500mg Natpro (3% cream) Progesterone Cream per day
* 2000mg N-Acetyl-Cysteine (NAC) per day
* 2000mg Taurine per day
* 5000iu's Vitamin D3 per day
* 1000mg Bioflavanoids per day

You are also in Peri-Menopause which can be a difficult time for most women.

Have you had your vitamin D3 level tested? Vitamin D3 is very important, a deficiency reduces the benefits of progesterone. Nothing less than 5,000iu's per day is needed. Optimal range is between 70-100ng/ml. Magnesium and vitamin K2 with no soy are important co-factors needed when taking vitamin D3.

Jan 02, 2019
Thank you
by: Anonymous

Thank you for taking the time to write back!
You’re a blessing!!!


Jan 24, 2019
Correct dosage?
by: Anonymous

Hi, I also wonder if I'm taking enough prog or maybe too much?

I'm 50, had hysterectomy 3 years ago. In Aug I started to gain weight and have terrible hot flashes. I eat almost all organic and mostly veg, and exercise a lot. I've stayed very fit. I started taking the creme in Dec. I use about 120/125 mg, divided in half each day. I also use just a touch of estrogen creme in the am. My hot flashes ceased immediately but I gained another 10 pounds since then. I'm horrified! I feel like a blown up balloon. None of my clothes fit.

I understand from your site that a balancing act needs to happen with my hormones and my weight, hopefully will come back down. My question is, at this point, my only issue is the weight. Should I increase the prog more or wait more time?
Thank you.

Jan 28, 2019
Correct Dosage
by: Joy

Hi there

You are in Menopause which can be a difficult time. I don't believe that you are using enough progesterone. Try increasing to 200mg per day and see if that helps you. You may need to use more especially if your Hot Flashes return. You have only been using progesterone since December, it can take between 2-6 months before the body adjusts, progesterone therapy does take time.

Click here to add your own comments

Join in and write your own page! It's easy to do. How? Simply click here to return to Progesterone faq.

Share this page:
Find this page helpful? Please tell others. Here's how...

Would you prefer to share this page with others by linking to it?

  1. Click on the HTML link code below.
  2. Copy and paste it, adding a note of your own, into your blog, a Web page, forums, a blog comment, your Facebook account, or anywhere that someone would find this page valuable.

Search over 8,400 pages on this site...