by Maria Brianis

Hi,please excuse my bad english. I suffer post partial psychosis 2 months after childbirth, taking psycholeptic Zyprexa 10mg for about 1month. Found out that levels of progesterone are low. If i start progesterone should i quit with psycholeptics? What dose progesterone cream do you recommend in my case. My psychiatrist doesn't know about progesterone therapy in PPP at all. Thank you, Maria

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Dec 10, 2012
by: Wray

Hi Maria Your English is fine! Progesterone can help PPP, but very large amounts are needed. If it is PPP, rather than post natal depression, then amounts up to 2400mg/day were given by Dr Dalton to her patients. She wrote a book called 'Depression after Childbirth', which covers all forms of depression. It really is worth getting, Amazon sell it here. You could also look at a page we have here, which gives a brief overview. It's always safer to start progesterone first and use it for at least a month before beginning to reduce any drug. We do have a page on how to reduce, please see our page on Natural Antidepressants. We also have a page on Anxiety. It gives a list of all the nutrients which help depression. It's best if you could start these too before reducing. Zyprexa can cause diabetes, so please be careful with this drug. If you bought Dr Dalton's book, your psychiatrist might be willing to read it to gain a better understanding of progesterone and PPP. Unfortunately Dr Dalton died a few years ago, so he can't ask her any questions. But the book is very comprehensive. You might not need 2400mg/day progesterone, particularly if you starting taking the natural antidepressants too. Please come back to me if you have other queries. Please have a vitamin D test done, it's always low in depression. Plus your baby needs it too. Please see the videos we have at the bottom of our Pregnancy page. For more info on vitamin D levels, test kits etc see the Vitamin D Council, GrassrootsHealth and Birmingham Hospital. Blood levels should be 70-100ng/ml (175-250nmol/L) and not the 30ng/ml (75nmol/L) most labs and doctors regard as adequate. The minimum daily dose should be 5000iu's per day, although recent research indicates it should be 10,000iu's per day, see here. Take care Wray

Dec 12, 2012
by: Maria

Thank you so much.
Do you think injections of progesterone better in my case?
Taking 3000iu vit D3 already , also vit B, magnesium, selenium.

Dec 13, 2012
by: Wray

Hi Maria Although I said 2400mg/day was given by Dr Dalton to her patients with PPP, I think you could start off with 400mg/day. Injections are large and painful, and only come in 50mg doses. Which would mean you would need 8 injections per day just to get 400mg. The cream is far nicer to use, and it can be applied anywhere with no pain! In fact progesterone is an excellent anti-inflammatory so can be rubbed into painful areas. Please increase your vitamin D to at least 5000iu, this is only a maintenance dose too, it won't raise levels as quickly as I think you need. Glad you're taking the magnesium, it's the most important co-factor for vitamin D. Take care Wray

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