Progesterone, spotting before period and infertility

by Laura
(NYC )

I am 39 and have been trying to conceive our first child for a year now. While on birth control (Yasmin) I started spotting one week to 10 days before my period. Since I stopped birth control I have been monitoring ovulation, I ovulate between cd12 and cd14 of a 28 to 30 day cycle.

Still I have spotting (brown, just a little, I am ok with a panty liner) 2 to 10 days before my period, it usually stops the day before the period. My periods are also very light and last for 3 days only.

I have recently being diagnosed with hypothyroidism (Hashimoto's) and I am taking 25 mcg of synthroid. A hysterosalpingogram showed no abnormalities in my uterus and tubes. These are the results of my blood tests:
Day 3 Fsh: 6.32 mIU/ml
Lh: 5.80 mIU/ml
Estrogen: 46.4, sorry I don't know the units of this
Day 21 Prog: 24.1 pg/mL
AMH: 6.23 ng/mL
TSH: 2.93 mIU/L (7/22/11)
2nd TSH: 3.39 mlU/L (8/5/11)
Free T4 1.2 ng/dL
TPO ab: negative 24 IU/mL
Thyroglobulin ab: positive 80 IU/mL
3rd TSH: 2.03  (9/14/11)

My day 21 progesterone was indicative of ovulation so my dr. was not concerned about the spotting but I would like to know if progesterone cream would help me reduce or eliminate the spotting between periods.

Has anyone used it for this purpose? How should i use it? Could it help us trying to conceive?

Thanks a lot!!!

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Oct 22, 2011
Progesterone, spotting before period and infertility
by: Wray

Hi Laura The one test they didn't do, which to my mind is the most important, is vitamin D. This is essential for normal ovarian function, for ovulation, a successful pregnancy and the growth of the foetus, see here, here, here, here and here. These are excellent videos to watch too, see here and here. Vitamin D is also essential for a normal functioning thyroid. Please have a test done, for more info see the Vitamin D Council, GrassrootsHealth Birmingham Hospital and Vitamin D Links websites. Blood levels should be 70-100ng/ml and not the 30ng/ml labs and doctors regard as adequate. The minimum daily dose should be 5000iu's per day. Your progesterone is indicative of ovulation, but spotting is not a good sign. It means the lining is breaking down before it should, no embryo would implant in such an environment. MMP's are enzymes that break down the lining at the end of the cycle. They are stimulated by oestrogen, suppressed by progesterone. It would appear that perhaps the MMP's are too high. Progesterone is also essential for Pregnancy. It normally stops the spotting, but initially you would need a high amount. I recommend 100-200mg/day, but would suggest you use the higher amount for a month or two. But before you consider it please read our page on Oestrogen Dominance first. For more info please see our page on How to use progesterone cream. Take care Wray

May 26, 2015
by: Anonymous

My story is exactly the same word for word except I would suggest getting off of synthesis as it only works in 2% of the population and get on the bioidentical thyroid hormone "Armour". No side effects like the manufactured kind and safe. Been in use since the 1950s. My hormone doctor recommended progesterone but my obgyn says to only take it 7 days after ovulation. Confusing!

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