Progesterone for infertility

by Ellie

This website is an amazing treasure trove of information! I'm grateful to have found it as my husband and I are trying to conceive (TTC) our 3rd child. After a chemical pregnancy in February, I started seeing a naturopathic doctor and was told I have low progesterone.
My cycle is currently 24-26 days with a couple days of spotting before bleeding. Mood swings, weak ovulation/anovulatory cycles and weight gain have been other issues I've dealt with.
I have tried progesterone cream a few times in my TTC journey with no success. I just recently learned I've been using far too little to even make a difference (20mg/day of the progesterone cream by Emerita).
At cycle day 23, I started using 70-100mg/day. It was hard to be consistent because the cream was so sticky and didn't absorb well. I started spotting the next day but continued using the cream and was surprised and pleased to see that the spotting was a little less and my period held off until I'd completed a full 28 day cycle. It's been months since I had a 28 day cycle, and that was with acupuncture.

I'm hoping to switch to the Natpro next cycle. Should I start with 50mg am/pm and slowly increase, or should I start with a higher dosage since I was still spotting last time?

Comments for Progesterone for infertility

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Aug 24, 2022
Progesterone for infertility
by: Joy

Hi Ellie

Thank you for your kind words. Progesterone is the pregnancy hormone, if it's low conception could become a problem. Progesterone must only be used at ovulation if pregnancy is the aim. It should be used during your luteal phase which is always, in all women, 12-14 days long. Progesterone is used during this luteal phase. Stress could also be a contributing factor. It lowers progesterone levels as well as vitamin D3 and other valuable nutrients. The Pregnancy page will explain in more detail.

As you are battling with ovulation and anovulatory cycles it is recommended that you use progesterone every day with NO breaks until this improves and a regular monthly cycle returns. Then use the cream by following your cycle i.e. luteal phase. Please read the Menstruation page. If progesterone is not used correctly it will not help you. Please do not start on 50mg, between 100-200mg is needed as stated many times on this website. Use a good organic progesterone cream such as Natpro which is a 3% cream. If using another cream, please adjust so that it equates to Natpro. Natpro absorbs extremely well and can be used anywhere on the body. Is excellent when inserted in the vagina at night. Helps with dryness and inflammation. When first using progesterone, the body will react in a number of ways, it could be spotting, aches pains etc. This is normal as progesterone becomes the dominant hormone, it must be dominant at all times. Please read the How to use Progesterone Cream page as well as the Estrogen Dominance page as you are also suffering from this.

Vitamin D3 is important and the level must be optimal at all times. A deficiency reduces the benefits of progesterone and is connected to every single function cell in our bodies making it vital. If a mother is deficient in D3, it will be passed onto the baby.

Aug 25, 2022
by: Ellie

Thank you for the response, Joy, and thank you for more helpful information!
I have my NatPro in the mail and look forward to starting 100-200mg per day beginning at ovulation.
I'll do more reading through the articles you recommended. Thank you!!

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