Progesterone and THC.

by Toni

My doctor wants me to try medical marijuana for severe insomnia. I have been on a high dose of sublingual bio-identical Progesterone for sleep for a couple of years and want to get off of it. The symptoms of Progesterone that I hate are foggy brain, fatigue and worse insomnia when I try to lower the dose, it feels addictive.

My question is this. Since Progesterone is a natural MAOI can it safely be combined with THC? I am on 650 mgs. of Progesterone now and have had a very difficult time reducing the dose.

Thank you.

Comments for Progesterone and THC.

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Nov 19, 2017
by: Sharon H.


Your Thyroid plays a role in sleeping as well. Even if your numbers are in the low normal range, it is enough to effect your sleep. Maybe get it checked? I use medical marijuana to help sleep, and it does help. It does not effect your progesterone.

Nov 20, 2017
Progesterone and THC
by: Joy

Hi Toni

Progesterone does not interfere with any drug or natural product, it should not interfere with THC.

While the correct use of progesterone can help with mild insomnia, it does need help if severe. I used to suffer from terrible insomnia and it was not until I started to understand the benefits of Vitamin D3 and Magnesium that I no longer suffer from it, thank goodness! Do you know what your vitamin D3 level is? A deficiency reduces the benefits of progesterone and is connected to every single functioning cell in our bodies. Please consider trying.

Oral progesterone is not the best delivery method as 96% gets destroyed by the gut and liver which means that you are getting very little progesterone. The symptoms of progesterone that you describe are actually estrogen dominance symptoms and the correct use of a good organic cream such as Natpro will help you greatly. Fatigue could also mean insulin resistance have you been tested for this?

I see that Sharon mentioned the thyroid, have you had yours tested and are you taking iodine? Thyroid issues are also linked to a vitamin D3 deficiency.

Please read these pages and the references as they will explain things in more detail.

How to use Progesterone Cream

Estrogen Dominance

Vitamin D3


Insulin Resistance

Progesterone Delivery Methods

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