by JL

Hi Wray,
I have just come across this blog a couple of days ago and am very impressed by the information it provides! I have bought one portion to give a try. I am 53 and have scored on the test with 41 point. I understand I can expect improvement with vains, depression, body temperature and other issues. I am planning to ask my GP to do the blood test, so that I have a clear starting point.

What I do not quite understand is : what does it mean: NATURAL progesterone (vs.synthetic). How is it being produced and how come it is beneficial and has no side effects as HRT?

Kind regards,
JL, Holland

Comments for JL

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Apr 16, 2012
by: Wray

Hi JL Thanks for the kind words! Progesterone can help with a great many problems, but it is essential to use enough. Too many women are advised amounts so low they merely feel worse. And then suffer permanent Oestrogen Dominance. I recommend 100-200mg/day or more, it's so dependant on how bad the symptoms are. For more info please see our pages on Peri-menopause and Menopause. We have many women using 400-500mg/day, and a few using 1000mg/day. Progesterone is synthesised in the body from cholesterol, the major portion being made in the ovaries. But our adrenals, brain and glial cells also make small amounts. Progesterone can be synthesised in a lab too, the end result being the same molecule as that the body makes. Progestins are then made in the lab from progesterone, as are oestrogen, testosterone and cortisol, see here. The progestins were made because oral progesterone is mostly destroyed in the gut and liver. So could not be used for any drug based Contraceptive. Unfortunately to enable them to be taken orally and not be destroyed, the molecule is greatly changed. So much so it barely looks like progesterone! Why are there no adverse side effects, I think this is best explained on our page Progesterone Misconceptions, there's more info on our Menstruation page too. The main difference is progesterone is a potent analgesic, anti-inflammatory and anxiolytic. Whereas oestrogen is an excitatory, inflammatory hormone. It's also a mitogen causing cells to proliferate, hence it's danger in HRT. Progesterone inhibits mitosis, so has been used successfully in some Cancers. Take care Wray

Apr 18, 2012
by: Wray

Hi JL I'm pleased it arrived so quickly! If you're using Natpro, you'll need 6ml of cream to get 200mg/day progesterone. We do have more info on measurements right at the bottom of our page on How to use progesterone cream. If you're using another cream, please come back to me about the strength, then I can work out how much you need. Take care Wray

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