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Is the 200 mg progesterone daily dose good enough?

by samyra

Good afternoon!
Please forgive me if my English isn't that good, once it isn't my mother tongue.
First of all, I'd like to say that the kind of work being done here is simply amazing and it makes a difference in people's lives. Well, Wray, please help me...I have had a spontaneous miscarriage and I think it was due to my low progesterone levels. I took progesterone during my luteal phase and stopped on day 27 of my cycle to wait for menstruation. I started taking progesterone again as soon as I found out pregnancy, but it didn't work. The embryo didn't develop. After not taking progesterone for 5 days I re-started it but I think it was too late. My doctor told me that wasn't the reason why I had a miscarriage because she believed there would be some "residual progesterone" left that would have been able to support the very beginning of the embryo development during this "pause". Now, I'm trying to get pregnant again and I'm taking Utrogestan - 200 mg once a day. My doctor told me I should keep on using the same dose and allowed me to use it until I was sure about being pregnant or not. She also told me to keep on taking the same dose (200 mg)after I get pregnant. Well, I had been taking it orally, but I've read it isn't the best way for the progesterone to be absorbed. My current progesterone level (with the 200 mg dose I've been taking) is 6 ng/ml (or 20 nmol/l). I think it is too low and asked my doctor to double the dose if I get pregnant (400 mg a day), but she said I shouldn't do that because she believes it could cause female formations to a male fetus-baby. What should I do? Shoud I take 200 mg or 400 mg? Is there any possible harm to the baby if I increase the dose? Thank you so much for reading everything!

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Jan 14, 2012
 Is the 200 mg progesterone daily dose good enough?
by: Wray

Hi Samyra Thanks for the kind words, and your English is better than most! I suggest using the Utrogestan as a suppository in the vagina. Alternatively you could open the cap and add the contents to a small amount of cold pressed oil, or a natural skin cream. Then rub this on your skin, incidentally it's wonderful for the skin. That way you will be getting the full benefit of the progesterone, and probably won't need the 400mg. I don't believe there would be any 'residual' progesterone left, particularly as you were taking it. Oral progesterone is not the best Delivery system as most gets destroyed in the gut and liver, leaving little to enter circulation. One thing progesterone can't do and that's cause female formations in a male child! If it did, then every male child born would have female characteristics, as we make over 400ng/ml per day during the third trimester. Progesterone is as vital for males as it is for females, it's not a female hormone, and it's not a sex hormone. In fact male babies have more progesterone receptors than female babies, it appears to be needed for testicular hormones to masculinise the brain, interesting! See here. We do have a page on Pregnancy which explains how to use progesterone, how much and when too. Please have a vitamin D test done, this is as vital for a successful pregnancy as is progesterone, see here, here, here, here and here. These are excellent videos to watch too, see here and here. A lack has also been implicated in miscarriages, see here, here and here. Continued below.
Jan 14, 2012
 Is the 200 mg progesterone daily dose good enough? Part 2
by: Wray

Hi Samyra For more info on vitamin D levels, testing etc see the Vitamin D Council, GrassrootsHealth, Birmingham Hospital and Vitamin D Links websites. Blood levels should be 70-100ng/ml or 175-250nmol/L and not the 30ng/ml or 75nmol/L most labs and doctors regard as adequate. The minimum daily dose should be 5000iu's per day, although the latest research indicates it should be 10,000iu's per day, see here. Take care Wray

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