Irregular cycle and starting progesterone cream too early

Hi, I am currently trying to conceive my second baby. I'm still breast feeding 2x a day so my cycles are a bit irregular. My lp is consistently 8-9 days so my Dr. prescribed me 50mg of progesterone cream, starting when I get my first positive opk (directions on the bottle say day 14 to 21).

Well I thought I got a positive so I started using the cream and kept using the opks. Two days later I got a super dark line so now I'm thinking the first was close but not actually postive. That was 3 days ago. Now I'm worried I've totally messed up my cycle and the progesterone is going to stop me for ovulating since I started it too early.

Do I still have a chance this month and should I keep applying the cream or stop?

Comments for Irregular cycle and starting progesterone cream too early

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Aug 14, 2017
Irregular cycle and starting progesterone cream too early
by: Joy

Sadly you haven't been advised on how to use progesterone correctly so you will probably battle. For a start you do not have regular cycles, secondly nothing less than 100mg should be used. The cream used is also very important, is it a compounded cream? Most creams do not have the correct progesterone concentration. What concentration is the cream that you are using? Progesterone should be used for 14 days prior to ovulation or within the 50 hour surge of progesterone which occurs prior to ovulation.

As your cycles are a bit irregular, this can be difficult. Just so that you are aware, home test kits for pregnancy are notoriously unreliable in the very early days. If pregnancy is suspected, progesterone should NOT be stopped. There is more information on this on the Pregnancy page. May I suggest that you also read the 'How to use Progesterone Cream' page as well.

The spotting is caused by the body adjusting to the progesterone, it does take time to settle down, in spite of the amount you were using. It usually takes 2-6 months for the body to adjust to progesterone therapy. Your cycle will become a little messed up when first using, but again, the amount that you have been advised to use is incorrect and will cause problems for you. Did you doctor not tell you to expect your cycles to go crazy in the beginning? Usually menstruation is not likely to return to normal until after breastfeeding has finished.

What is your Vitamin D3 level? A deficiency reduces the benefits of progesterone and is vital for the pregnant mother and the unborn child. Co-factors are needed when taking vitamin D3.

Please read these pages and the references:
How to use Progesterone Cream

Estrogen Dominance


Dr Kittie Dalton

Vitamin D3


Aug 15, 2017
In response
by: Anonymous

What I was prescribed is a compounded cream 5% solution. I'm not spotting or anything, I was just worried because I ran out on Saturday. The prescription was only enough for those 7 days and I was concerned that by stopping I would induce a period which would obviously ruin our chances of conceiving this month. Hopefully since it was such a small dose it won't have any effect?

I have chronic low D3, have for years. I take 50,000 IU e 2x a week and 10,000 IU on the days between large doses. My last check was 2 weeks ago and my levels were in the 60's.

Aug 17, 2017
In Response
by: Joy

Please make sure that the compounded cream does not come mixed with estrogen and or testosterone, chemicals and parabens. This is not what any women needs, it defeats the object of making progesterone the dominant hormone. A good organic progesterone only cream would be far better for you and everyone else for that matter. I take it that you are taking the co-factors when taking vitamin D3 as mentioned in my post above.

Aug 19, 2017
What now?
by: Anonymous

The progesterone cream I was prescribed doesn't contain estrogen or testosterone. My 50,000 iU of "D3" I was prescribed is actually D2 😞
I also have 10,000 iu of D3 that I take on the days between the big doses. I take magnesium everyday (2 tsp of natural calm powder). I'm still taking my prenatal that has vit. A and vit. K (smarty pants brand).

My lp was only 8 days again this cycle. Whats the best brand of progesterone cream? What dosage do i need? I plan on using it once I confirm ovulation with my bbt and then use it until I take a test at 14 dpo.

How can I expect this to mess up my cycle? I really hope it doesn't take 3 to 6 months for us to concieve!

Thanks for the help.

Aug 19, 2017
by: Anonymous

I also take 500mg of Vitex

Aug 21, 2017
Now what?
by: Joy

Well it seems to be a common thing that doctors and pharmacies like to do, prescribe D2 instead of D3. Now I do not know if that is done deliberately or not, but they know full well what is needed. I would take that back and ask them why they gave it to you! I also do not agree with big doses either, it should be kept constant, either 5,000iu's or 10,000iu's depending on how deficient you are, and must be taken every day. I have no knowledge of natural calm, preferring the ones listed on the pages given to you. If it works for you then great, as long as you are benefiting and getting the required amount per day. Vitamin K2 must be with NO SOY.

I can only recommend Natpro Progesterone Cream. It was formulated over 20 years ago and is exactly what the body needs, no added chemicals or parabens and nasty things that can cause irritation. As advised above, it must be used every day for 2-6 months with no breaks. I have given you the pages to read up on. Your body has to adjust and become balanced before you can conceive. This could take 2 months, or 3 or 6 or longer, it all depends on how progesterone is being used and how much excess estrogen you have. Progesterone has to become the dominant hormone first before things improve.

Vitex is estrogenic, something that I would not recommend.

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