Interstitial cystitis and progesterone therapy.

by Aurora
(Las Vegas)

About two years ago I was diagnosed with Interstitial Cystitis. It took around seven years and six different urologists to finally be diagnosed with IC. Being able to be diagnosed gave me some sense of closure to my horrible symptoms but being told that there was no cure was, and has been, very disheartening.

After doing about a year of my own research I found a holistic MD who suggested oxygen therapy to the bladder and progesterone therapy replacement to help my symptoms. Finally a doctor that actually tested my hormones and I did have a big imbalance, in fact at the time I was producing zero progesterone.

This last month was the first time in over nine years that I have been pain free before my period, I believe the progesterone therapy is working, but I had a set back, I stopped the progesterone because I thought I had to give my body a break after my period started and a couple days later had one of the most horrible flareups I've ever had.

I am very confused on when and how to take the pill form of progesterone. I don't understand when I should take it during the month and when I should stop it during the month? My symptoms are horrendous the first week before my period. I have also been having flareup not before my period.

I want to try to stabilize myself. Is it too much to take progesterone everyday? Or should I take it the first couple days during my period then stop for 10 days? And how much should I take?

Sometimes I feel like I should take more for my symptoms to go away. But I stick to 50 to 150 ml. I need to get on a schedule and stick to it so I can see if it helps my symptoms. I feel like it might but I'm still in pain.

So confused, please help!!

Comments for Interstitial cystitis and progesterone therapy.

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Jul 03, 2018
There are answers for you
by: Anonymous

You need to see a hormone specialist. Ideally you find out why your hormones aren't balanced. There are so many reasons this could be happening. If you are forced to supplement then do so under the guidance of a specialist.

Jul 04, 2018
Interstitial cystitis and progesterone therapy.
by: Joy

Hi Aurora

Oral progesterone is not the best Delivery Method as so much gets destroyed by the gut and liver. Please consider using a good organic progesterone cream such as Natpro. Between 100-200mg progesterone is needed.

I suggest that you use progesterone every day until your cycle has become regular and you feel stable, then use the cream by following your cycle with your luteal phase. The cream should only be used from ovulation (Luteal Phase) for the last 14 days of the cycle. Should your symptoms return then perhaps you need to use progesterone every day. Please read How to use Progesterone Cream and Estrogen Dominance.

It is always a good idea to have hormones tested. The Hormone Testing page explains exactly what levels should be.

A vitamin D3 deficiency reduces the benefits of progesterone, please make sure that your level is between 70-100ng/mL. Co-factors need to be taken when taking D3, magnesium and vitamin K2 are the important ones.

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