How Does progesterone compare to DIM?

by Paul

I am a 65 year old male. I'm using 0.5gm of testesterone cream twice daily, 100mg. of 7-keto DHEA, and 20mg. of cortisol. I have fatigue, low libido, and E.D. and I also have COPD.

I had blood tests done after three months of therapy. My free T went from 7.5 to 3.8 and my estradiol went from 22 to 74. I'm now taking DIM to try and balance the estrogen.

How does progesterone compare to DIM? Which would work better, or would the combination of the two be better? How does progesterone work to balance the testosterone and the estrogen? I feel stronger now and my libido has improved but still have fatigue and ED. I sleep well and feel some improvement but I'm disappointed in the low free T. What would you recommend? Thanks.

Comments for How Does progesterone compare to DIM?

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Aug 21, 2009
How Does progesterone compare to DIM?
by: Wray

Hi Paul. I'm relieved you're taking 7-keto DHEA and not DHEA which can cause cancer. DIM is excellent at reducing oestrogen levels, so incidentally is progesterone, it effectively suppresses it. The two together would be a good choice.

Many men who have tried testosterone have switched to progesterone and found it more effective for fatigue, low libido and ED. As it's a vasodilator and anti-inflammatory it can also help in lung problems, particularly asthma. It also suppresses MMP's, (matrix metalloproteinases are enzymes implicated in COPD). The amino acid N-acetyl cysteine, a powerful antioxidant, is essential. Our intake declines with age. I would suggest you consider taking this (I take ±3000mg/day), plus vitamin D, a low level of which has been implicated in the development of COPD. Please have a look at the papers below:

N-acetyl cysteine
The Lancet Vit D & COPD

I received an email in November last year from a man who uses progesterone, I have pasted it below it case it helps:

"Hello Wray,

You asked me to report back to you once I had tried Natpro for a good length of time. I am one of your relatively rare male customers, aged 63, and was initially attracted to Natpro for two potential benefits: an improvement to my (benign) prostatitis, and an improvement to my libido. I am instinctively sceptical, and am not likely to be subject to the placebo effect - so I like to think!

Six months on I can report a definite and very welcome outcome in both respects. Whereas I used to have the usual difficulties associated with an enlarged prostate: poor flow and excessive frequency of urination, with consequently disturbed nights, I now routinely sleep soundly through six or seven hours, and the rate of flow, while not as vigorous as many years ago, is good and continuous.

As for the libido... let me simply say that I am delighted with the results in my sexual life. An entirely unexpected effect, and also welcome, was that very quickly (I mean within days of starting the applications) there was a marked effect on my sleep, which had been light and broken, but became heavier and more continuous and therefore more satisfactory, even though in those early days I was still having to get up once or twice to urinate.

So, many thanks indeed. You have an ongoing customer!
(Use this if you like, but anonymously, please)"

Take care, Wray

Jan 13, 2010
The amount of 7 Keto DHEA is still too high.
by: Amanda

I really believe the amount of the 7 keto is still too high and could be causing your side effects. You could try lowering the dose and see what happens.

Jan 18, 2010
The amount of 7 Keto DHEA is still too high.
by: Wray

Hi Amanda. It might be as the recommended dose is 50mg/day, although studies have used up to 200mg/day with no ill affect, please see this report. Take care, Wray

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