Age: 63. Hot Flashes day and night and fragmented sleep (Avg 5 hrs) for going on 7 years.
Third doc now. Have tried Progone,herbs,iodine,vitamins, minrals, homeopathics, topical progesterone,Prometrium, Vivelle dotpatch, and a few days ago, bioidentical testosterone and Biest vaginally,with oral progesterone 25mg time release. Had severe headache and worse sleeplessness with Prometrium 4 years ago, but current doc wanted to try the sustained release oral progesterone. After 3 days I was nearly crazy with worsening headache and no sleep. He said the only reason I can't take oral progesterone is that I might have an endometiosis implant in my brain. He said to stop the estrogens and testosterone,and progesterone but keep on DHEA. First doc 6 years ago (10/2007) checked only blood hormone levels and said mine was low. Started on Biest cream. Hot Fl cont. Second dr. checked saliva 5/28/2009 (Prog. 9127pg/ml,Estrodiol 14.3 pg/ml) and said I was in a bathtub of hormones and he wanted to titrate me down gradually.
Symptoms continued. Then he put me on Estridiol patch .075 biweekly and 30 mg topical prog. twice daily. Three mo. later saliva Prog 493 pg/ml, Estradiol 1.1pg/ml. I felt the best at this time than ever. Hot flashes almost gone. From then on, the symptoms came back, hormone levels on 11/30/11 Prog. 12,468 pmol/L, Estradiol 8.3 pmol/L. (I don't understand the switched measurements to pmol/L)
10/2012 I just switched to 3rd dr and now he tells me to get off all because I can't take the oral progesterone and too risky to take estrogens without it. He says urine hormone is the gold standard for hormone measurements. All my levels are low. (Pregnanediol 24 hr urine 0.39 micromol/24h,estradiol 0.5mcg/g Creat.,estriol 0.4 mcg/g Creat.) He has done lots of labs and thinks I have inflammation of gut which needs to be addressed, so I am on lots of supplements for that.
1.Is this wise to stop all prog. and est. at this time? The sleeplessness from 4am on continues and a few hot flashes day and night, though I could live with them as they are now. Have only been off all horms for a few days and in past when I've tried it, in a couple weeks, I am nearly crazy again.
2. Is there a way I could use those progesterone caps? I broke one and mixed with olive oil, but it is crystally like salt when I tried to rub it in ankles this morning.