by HealthAdvocate

I'm a healthcare provider. I'm interested to learn why your recommended Progesterone cream, NatPro, contains XANTHAN GUM, which is a source of PROCESSED FREE GLUTAMATE. So many of my patients are exquisitely sensitive to extremely small amounts of PROCESSED FREE GLUTAMATES, which is essentially the same as MSG. The reactions to PROCESSED FREE GLUTAMATE are the same as those for MSG, which can include but are not limited to anxiety, migraines, insomnnia, visual disturbances, nervousness, shaking, etc. - a wide range of symptoms. (While some may argue that the amount of xanthan gum is only "miniscule", (for extremely sensitive people, that's all it takes) why would the PROCESSED FREE GLUTAMATE in this product produce any less effect than a small amount of "paraben" in a product - and yet we know better than to use any product with paraben.) Glutamate functions as a neurotransmitter in the body. The body produces the correct amount that it requires for functioning. However, just like xenoestrogens, we are now being bombarded with PROCESSED FREE GLUTAMATE in so many every day products and in a myriad of forms. In excess, PROCESSED FREE GLUTAMATE acts as an excitatory neurotoxin. (Read the work of neurosurgeon Dr. Russell Blaylock and many others.) Nearly all neurodegenerative disease is linked to excess glutamate, including such diseases as Alzheimer’s, Amyotrophic Lateral Sclerosis (ALS), Multiple Sclerosis (MS), Restless Leg Syndrome, Parkinson’s, Epilepsy, Essential Tremor and many others. (Consider the drugs used to treat these conditions: Remacemide, Memantine, Riluzole, Lamotrigine, Budipine, Gabapentin, Lyrica, etc.; all of these drugs block the action of glutamate!) Certain genetic polymorphisms predispose some people to the buildup of glutamate in the body when ingesting exogenous sources of glutamate. An example of this kind of genetic defect is a polymorphism in the gene that governs the production of the GAD (Glutamate Decarboxylase) enzyme, which converts glutamate (excitatory) to GABA (inhibitory and calming). If a person cannot efficiently convert glutamate to GABA, there may be a buildup of glutamate to neurotoxic levels. Glutamate is also linked to eye disease such as glaucoma, macular degeneration and cataracts. It also plays a role in diabetes. Excess glutamate plays a role in so many diseases. And people are unknowingly ingesting it every day in so many products, including “supplements” that are supposed to be helping us, not harming us. I don't understand why any healthcare professional would recommend that anyone apply a transdermal product that contains yet another source of processed free glutamate. Fewer toxins may be absorbed when you ingest them than when they are applied to skin. According to evidence presented at 1978 Congressional hearings, absorption through skin may be 100 times greater than through oral ingestion. When toxins are consumed, the enzymes in saliva and in the stomach often break them down and they are flushed from the body.
Toxins that make it through to the kidney and liver are detoxified to varying degrees by enzymes before they reach the rest of your body. But, when toxins are absorbed through the skin, they bypass the liver and enter the bloodstream and tissues -- with absolutely no protection whatsoever. People are being exposed to increasing amounts of PROCESSED FREE GLUTAMATE in so many processed foods, cosmetics, toothpastes, shampoo, supplements, etc. - it is just as prevalent as xenoestrogens and in my opinion, just as dangerous. I hope anyone who reads this will research it all out for themselves! I'd love to hear your response. Thanks

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May 10, 2018
Xanthan gum
by: Justine

Good day

Thank you for your contribution and concerns.

Our head researcher and developer was well versed in the works of Dr. Mercola and Dr. Russell Blaylock. We stand fully with you in your argument against the use of and consumption of glutamate and acknowledge your well researched data on the effects of it. However I do need to inform you that NATPRO CONTAINS NO PROCESSED FREE GLUTAMATE.

The only argument against the use of Xanthan gum is that it may be produced by fermenting genetically modified carbohydrates/sugars, therefore derived form a GM source. The Xanthan Gum we source and use in Natpro is Eco Certified and certified NON-GMO.

The Environmental Working Group (EWG) data base, which Dr. Mercola references himself, is an authority on providing up-to-date and well researched information on so many products used in the world today, their report on Xanthan gum reveals that it is, "Not suspected to be an environmental toxin", "Designated as safe for general or specific, limited use in food", "Classified as not expected to be potentially toxic or harmful", "Classified as a low human health priority".

Irrespective of this, another point I need to make is this, and I quote a senior toxicologist with whom I am in correspondence:
"The molecular weight of Xanthan gum is stated to be between 4 and 12 million so it is not expected to be absorbed through the skin due to this high molecular weight."
Also see here:
"Based on the large molecular weights, the CIR Expert Panel determined that Xanthan Gum and Biosaccharide Gum-1 would not be absorbed through the skin. The CIR Expert Panel reviewed data that indicate that Xanthan Gum was not a reproductive or developmental toxicant. Studies of other polysaccharide gums did not reveal a genotoxic effect. Xanthan Gum and Biosaccharide Gum-1 were not considered to be dermal irritants or sensitizers."
Quoted from

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