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Estrogen upset my hormone balance

by Helena
(Canada)

I'm 44 and desperately want another child.

A little history. 1999-went off bc pills and had so many symptoms of menopause I thought I was going crazy. Took Estrologic for 2 mths. & it seemed to straighten everything out. Fell pg in 2000-had c-sect.Ectopic pg in 2002. Fell pg with 2nd in 2003-another c-sect. In 2007-miscarried. Saliva test in 2009. estradiol-result 2.1,range 1.0-9.9pg/ml. Progesterone result 91,range 50-250pg/ml. testosterone result 19,range 15-45pg/ml. The test was done in the luteal phase.

They said estradiol and testosterone were both in the low end of range. Would this cause a miscarriage? I know I ovulate because I take my temp and have a 14 day luteal phase but have noticed that I spot about 3 or 4 days before it actually comes. Last month I started taking the estrologic just after my period ended, then started 1ml progesterone cream at night 4 days after I ovulated. I got my period but I spotted 4 days before. It's weird but seems I feel better during my period and have more of a sex drive than any other time of the month. I'm taking the estrologic because I know I have symptoms of peri-menopause but I also want to have another child.

Do I really need to be taking it or will the progesterone cream alone level things out and if so how much should I actually be using now and if I do fall pg should I still use the same amout. As of now I am using a Progesterone cream (progesterone 100% pure usp grade-1134 mg per 2 oz yielding 6%derived from soy) I only have 1 jar left (the company has been shut down). I will be ordering progesterone cream from your company.

Just wondering are all progesterone creams alike? Thank you sincerely for any info you can share with me.

Comments for Estrogen upset my hormone balance

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Apr 28, 2011
 Progesterone cream dose and strength
by: Dan

Dear Helena,
This is the answer Wray gave me which will help you as far as dose strength etc.
Dan
21, 2011
Dosage amount of Progesterone Cream
by: Wray

Hi Dan This is a 1.6% cream, which means it contains 16mg progesterone per gram or ml of cream. 1ml is 5th of a tsp, which means 1tsp of the cream you have contains 80mg of progesterone. So 1/8th tsp contains 10mg of progesterone, 1/4tsp contains 20mg progesterone. Take care Wray
May 04, 2011
 Estrogen upset my hormone balance
by: Wray

Hi Helena All Contraceptives have the potential to cause adverse effects while taking them, and after stopping. So your symptoms don't surprise me. Interestingly every study I've read on ectopic pregnancies show progesterone is low. But not one of them looks at it as a possible cause, it's merely of passing interest! See here, here, here and here. A lack of progesterone is often a cause of miscarriages, not oestrogen or testosterone. Spotting before bleeding is an indication progesterone is dropping. The ratio of your progesterone to oestrogen is 43:1, which is low. We've found from Saliva Tests we run that the ratio should be 600:1 and over. Judging by your low ratio and the problems you've had, the ectopic pregnancy, the miscarriage, the spotting before bleeding, it appears your progesterone is too low. I recommend 100-200mg/day dependant on symptoms. I'm not sure how much you are currently using, but if less than this and you wish to increase the amount, please read our page on Oestrogen Dominance first, as this can occur. I always recommend starting progesterone before falling pregnant, to avoid having this whilst pregnant. We do have a page on Pregnancy, this gives you an idea of how much to use and when to use it. Progesterone comes in many Delivery systems, the amount varies considerably between them. The creams vary from 1.6% to 10%, occasionally higher from a compounding pharmacy. Take care Wray

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