Dosage Question

Hi Wray! I have a question, but this is the only place I can find to submit it! I am wanting to use 100-200 mg/day per your suggestion in the early stages of pregnancy. I just bought the new airless pump, which you say pumps 1.5 mL per pump. How does that convert to milligrams? Just trying to make sure I get the right amount based on number of pumps. Thanks!


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Nov 08, 2016
Dosage Question
by: Joy

Hi April

Any conversion website will help you, but if you read the How to use Progesterone Cream page, you will find a detailed conversion chart explaining this. One full pump of Natpro is 1.5ml or 50mg.

Sep 10, 2022
Efficacy and Progesterone Cream Strength
by: Anonymous

Hi. I have a question regarding strengths of creams. Recently, I added a 20% progesterone cream to my Natpro regimen. Ona’s is the brand and I thought this might be a good alt to running through product too quickly. I also upped my dose from 350 to
450mgs at the exact same time I started the Ona’s 20%. I was feeling pretty good before but still had some lingering ED symptoms I wanted to knock out. Immediately, night sweats came back which were gone for me along with several other miserable ED symptoms. I was surprised b/c I was already on a relatively high dose. I didn’t think I would experience this aggravation. I poured through this forum looking for something related and I came across an older thread where Wray spoke of doing an occasional "top up" (assume this meant taking more than her usual dose) and experiencing temporary ED symptoms. I don’t know what her daily dose was but I was under the impression that if one is stabilized on a dose then upping the dose would not make symptoms temporarily worse. Am I wrong on this? Would love your thoughts.

I also wondered if the Onas was truly a 200 mg dose. I did speak to someone over there and she told me that some women do not absorb the higher concentrations well. She actually said that 400 mg of a 3% cream is not necessarily the same as 400 mg of a 20% cream. I had no idea. She suggested adding an oil to the cream to possibly improve absorption. Have you ever heard of this? It is true that I don’t feel the Onas 20% is working like Natpro. My goal is to stay on a higher dose until I knock these symptoms. I don’t really like mixing brands but trying to find the best way to supplement. Thank you.

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