Do I need progesterone?

by Cindy
(Abu Dhabi)

Hi Wray! I am a 34 year old female. I started using Zoloft 6 months ago as I was experiencing anxiety, 'foggy head' and depression.

Zoloft is an antidepressant. It has helped but in the Luteal Phase I am still experiencing 'foggy head' and slight depression. I am not sure if I should include progesterone in my treatment. I do have a fibroid and have read that progesterone can help with this. Really just need answers or advice as to what to do. I do feel tired/lethargic in the Luteal phase and during menstruation. I am taking a vitB complex and Omega 3 as well.

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May 03, 2010
Do I need progesterone?
by: Wray

Hi Cindy. Seems as if your oestrogen is too high in relation to your progesterone. Progesterone peaks during the luteal phase as you probably know, oestrogen also rises too. So if you don't make much progesterone during that phase you will feel tired and anxious too. It could be you're not ovulating each month, as it's only after ovulation that we make progesterone. Progesterone really does clear a 'foggy head', don't I know! As that was one of my symptoms too, plus what I called 'early onset senile dementia'! My short term memory was so bad I couldn't remember a thing. Progesterone does help fibroids, as it suppresses the high oestrogen stimulating their growth, please see here.

Progesterone also helps to raise serotonin levels so helping depression. It also activates the GABA receptor sites, GABA is one of our most calming neurotransmitters, a low level leads to anxiety and panic attacks. You don't need the Zoloft, what you do need are the nutrients from which our neurotransmitters are made. The amino acid tryptophan is the precursor to serotonin, the B vitamin inositol helps raise serotonin levels too. GABA is also an amino acid, but a difficult one to administer, too much and symptoms come back, I prefer to work with progesterone to raise GABA levels. We do have a web page on anxiety, please see here. If you do decide to use progesterone, I recommend a cream as the best delivery system, it can be used anywhere, and the dose adjusted to suit symptoms. For more info on how to use it please see here. And please read the web page on oestrogen dominance as this can occur and is very disconcerting if it does! Take care, Wray

Aug 23, 2014
by: Anonymous

I wish I had known about progesterone many years ago as I have been 90kg and no matter what I do, eat, nothing changes my puffy weight...when I went to the Doctor at age 40, my hormones were so out of wack that I had no choice but to go back on the Pill. He said to me if I had one cancer cell I would have been dead in no time at all due to the high of my hormones

My weight has stayed the same for the last 12 years and I constantly feel puffed up. I do not eat wheat, dairy, preservative or oily foods but still no weight has come I am trying the Progesterone creme for the first time so see what occurs. I was always size 10 now I am size 16.
Everyone says to me how come you are so puffed up? I do not smoke or drink. Nothing helps so I pray that this may give me some life back.

Aug 25, 2014
Help me Progesterone
by: Joy

Hi Wendy

You are suffering from and going back on the pill has added to your problems. All drug based Contraceptives have a potential to cause harm. When using progesterone for the first time it is important to use nothing less than 100-200mg, possibly more if symptoms are severe, of the correct progesterone concentration per day. Using too little progesterone causes weight gain. It is not an overnight fix so patience is needed. You might light to look at the How to use Progesterone Cream, Peri-Menopause and Menopause pages too.

The Ketogenic Diet is excellent for loosing weight, perhaps you could try it? Do you know what your Vitamin D level is, as a deficiency reduces the benefits of progesterone.

Hope this helps.

Jan 28, 2015
by: Anonymous

I am 53 and now menupausing. No more female cycles. So happy with that being done. But now, I was taking a cream to help with hot flashes, but that is gone too. Still happy. Do I need estrogen and progesterone to keep my body happy and healthy. I don't want my cycle back. Hello, who really does? Can you advise me on what I need to do now. Thank you

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