Could progesterone cream help?

I am a 54 year old female, and one year ago I had surgery to remove endometrial tissue from my intestines. I had no symptoms of endometriosis until I started to have periodic symptoms of intestinal blockage (from scar tissue from the endometrial tissue that bled monthly). During this time I had 3 (3 mo) shots of depro-provera to supress menstruation and the gynecologist predicted that I would never resume menstruating.

Nine months after the last depro shot, I started menstruating again and have been having irregular bleeding (usually every two to three weeks for the last 9 months.) My estrogen level (as measured by blood tests) is still normal (9, I think) so I am not "approaching menopause."

My problem is this... I do not know if I have more endometrial tissue scattered about on my intestines, and am worried that if I continue to menstruate I could develop more scar tissue and blockage problems. I do not want to have more depro-provera shots because I have already suffered some bone loss. Is there a way to use progesterone cream to suppress menstruation? If I could cut down the bleeding to every couple of months instead of twice a month, I would be much happier. Thank you for your help.

Comments for Could progesterone cream help?

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Feb 14, 2008
by: Wray

Hi there, Progesterone doesn't normally suppress menstruation, even if using it continuously, it merely disrupts the cycle somewhat. But it has been shown to be a useful therapy for endo. I need to send you papers to show this, but can't do so on this site. Would it be possible for you to send me an email from the 'contact us' button, option 1? Thanks, take care Wray

May 08, 2009
by: Anonymous

I am a 33 yr old female who is about to undergo laproscopic surgery in 2 weeks due to endometriosis... multiple edometriomas (blood-filled cysts) were found on my left ovary.

This has been an ongoing problem for years now... I am highly against taking the birth control pill but my doctor stongly urges me to because he wants to suppress my periods because he says my uterus/ovaries need a "break". He says if not, then this could lead to long-term damage (no child-bearing or possible hysterectomy).

I think I understand this reasoning but I was wondering if progesterone cream, taken continually, would suppress my periods? I am really concerned about having periods now because of the build-up of these cysts that have happened. What do you recommend?

May 12, 2009
by: Wray

Endometriosis is caused by high oestrogen levels which stimulates the growth of the tissue, as are fibroids and cysts. I prefer to try a more natural approach before surgery. All three of the above respond to progesterone, although endo itself is a far greater problem than the other two and can become resistant to progesterone therapy in an older woman.

We do have a web page on endo you might like to look at:

Please don't take the BCP, the dangers are not worth it, we have another web page on this:

It's not a question of suppressing your periods, they have nothing to do with it. What does need to be suppressed is the excess oestrogen you are making. The Pill contains both synthetic oestrogen and a 'progestin' which is a synthetic progesterone.

Oestrogen and only oestrogen can stimulate cells to multiply and grow. Vital at puberty, without it we would not have breasts, hips and a layer of fat. Vital in the follicular or beginning phase of the monthly cycle, as it causes an egg/eggs to grow and mature and the lining of the uterus to grow. But an excess is dangerous as it stimulates hormonally sensitive tissue beyond the norm. It also suppresses progesterone, which causes the endometrium to stop growing and turn into the proliferative stage, making it ready for the fertilised ovum to embed itself. With inadequate progesterone there is nothing to prevent the oestrogen from stimulating cells endlessly, as in the case of endo, fibroids and cysts. Take care, Wray.

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