It is well established that the death rate from the coronavirus is highest amongst the already sick, weak and elderly. In other words those with an already compromised immune system. So although there is no known current cure there certainly is a defence... strengthen your own immune system!
There are many ways to do this that can be implemented individually, without the intervention of healthcare practitioners (these should of course be consulted immediately if symptoms present themselves).
This page seeks to provide you with useful frequently updated information resources from authoritative researchers, institutions and medical professionals. Just follow the links below.
But what has this to do with progesterone therapy? Simply put, there is a wealth of evidence clearly indicating that a deficiency in progesterone compromises the immune system. For this reason many of the links below will take you to papers in support of this established fact. We trust you will find them of value.
Does vitamin D deficiency increase the severity of COVID-19?
"If vitamin D does in fact reduce the severity of COVID-19 in regard to pneumonia/ARDS, inflammation, inflammatory cytokines and thrombosis, it is our opinion that supplements would offer a relatively easy option to decrease the impact of the pandemic."
Inhibitory effects of Vitamin D on inflammation and IL-6 release. A further support for COVID-19 management?
"Novel interesting findings suggest that vitamin D, by inducing progesterone-induced blocking factor (PIBF), might regulate the immune response and also modulate cytokine IL-6, which appears to be increased in COVID-19 infections."
Estradiol, Progesterone, Immunomodulation, and COVID-19 Outcomes
"Severe outcomes and death from the novel coronavirus disease 2019 (COVID-19) appear to be characterized by an exaggerated immune response with hypercytokinemia leading to inflammatory infiltration of the lungs and acute respiratory distress syndrome. Risk of severe COVID-19 outcomes is consistently lower in women than men worldwide, suggesting that female biological sex is instrumental in protection. This mini-review discusses the immunomodulatory and anti-inflammatory actions of high physiological concentrations of the steroids 17β-estradiol (E2) and progesterone (P4)."
Progesterone may reduce COVID-19-related inflammation
A new proof-of-concept study will examine the role of progesterone in reducing inflammation caused by COVID-19. This was the top story in endocrinology last week.
“We showed that even though COVID-19 is caused by a new virus, in an otherwise healthy person, a robust immune response across different cell types was associated with clinical recovery, similar to what we see in influenza,” Professor Kedzierska said. “This is an incredible step forward in understanding what drives recovery of COVID-19. People can use our methods to understand the immune responses in larger COVID-19 cohorts, and also understand what’s lacking in those who have fatal outcomes.”
Study examines progesterone to reduce inflammation in COVID-19
Of the many complications reported to accompany COVID-19, one of the most vexing to researchers has been the “cytokine storm,” or the body’s overactive immune response to a viral infection. The phenomenon — observed in some patients, but not others — can complicate clinical decision-making during a time when there are no treatments and no vaccine. Researchers are searching for possible therapies that may inhibit inflammation, such as the sex hormone progesterone.
Progesterone and Autoimmune Disease
Prevents autoimmune disease because it modulates immune function, reduces inflammation, and up-regulates detoxification enzymes.
How Bioidentical Progesterone Can Help Autoimmune Disorders
Effects of progesterone Progesterone boosts the immune system. It is also neuroprotective and helps stabilize blood sugar.
Female-Dominant Autoimmunity: The Role of Progesterone. Progesterone & the Immune System
Progesterone Function: Role and Effects
Top 12 Ways to Guard Against Coronavirus. Boost your immune system.
Progesterone has been shown to have direct effects on immune cells, thereby boosting the immune function.
Sex hormones and the immune response in humans
Steroid Hormones and Their Effect on the Immune System
Coronavirus: How to Boost Your Immunity
Progesterone-Based Therapy Protects Against Influenza by Promoting Lung Repair and Recovery in Females
A functional relay from progesterone to vitamin D in the immune system
Effect of progesterone on the immune system in consideration of bovine placental retention
Progesterone-based compounds affect immune responses and susceptibility to infections at diverse mucosal sites.
Progesterone promotes healing in the lung after a bout of flu
The Coronavirus Is Not Causing Deaths - Weak Immune Systems Are