Can I take progesterone suppositories my entire pregnancy?
I am wondering about continuing progesterone throughout my entire pregnancy. Right now I am 16.5 weeks pregnant and have been taking 200mg per day of bio-identical progesterone.
I have had 3 consecutive miscarriages at 12 weeks, 8 weeks, and 16 weeks. After my first loss, I had a hunch that progesterone was the problem. So, for the next pregnancy, I found over-the-counter natural progesterone cream. That didn't work. In between pregnancies I began having symptoms that I had never experienced before. From ovulation to period I would have anxiety and cramping. Both of those would stop when my period started. For the next pregnancy, I asked a doctor to prescribe bio-identical progesterone suppositories. I was on 100mg per day. At 12 weeks, I was advised to wean myself off. By 14 weeks, I quit taking progesterone.
At 16 weeks I went in for an appointment, and they couldn't find the heartbeat. An ultrasound confirmed that the baby had passed away. Based on the baby's measurements, the doctor guessed that the baby died at about 14 weeks, which is when I stopped taking progesterone.
After that third loss, I went to an infertility clinic to figure out what kept going wrong. She tested me for everything she could think of. Her final thoughts were that I have diminished ovarian reserve based on an FSH of 10.5 when it shouldn't be over 10. She thought that maybe I'm putting out bad eggs, the bad eggs are getting fertilized, and the pregnancy doesn't last. However, she said that doesn't explain my second trimester loss. Her conclusion definitely doesn't resonate with me, and I don't think it's what was causing my problems.
After some time of tying to strengthen my body, we began trying again, 8 months after that last loss. We got pregnant in 3 months with the baby I am pregnant with now. The infertility dr. wanted to put me on a synthetic progesterone of 200mg per day. I asked for bioidentical instead, and she said they wouldn't be able to do that or even give me a prescription for an outside pharmacy. It's very important to me to get bioidentical, so I went to a naturopath. I told her my history, and she said that I should have never stopped the progesterone. She recommended that I take progesterone this entire pregnancy.
She gave me a bioidentical progesterone in oil to apply topically. I didn't that for about 3 weeks and then switched to a sublingual progesterone. With both, I was continuing to have my low-progesterone symptoms: mild cramping and anxiety. After maybe 2 weeks of the sublingual progesterone, I asked another doctor to prescribe bioidentical progesterone suppositories. He prescribed 200mg per day.
I have been taking that since maybe 8 or 9 weeks pregnant. The cramping went away. Every once in a while I will have a little bit of anxiety, but definitely not as often as before. Now, I'm 16.5 weeks pregnant, and all the health professionals around me aren't sure what to do about the progesterone. Everyone says the same thing: "the placenta should take over by now." I'm definitely not comfortable coming off the progesterone. I want to do what's best for the baby and this pregnancy, but I'm not sure what that is.
Can you give me advice about whether or not to stay on the progesterone for the whole pregnancy?