Calcium D-Glucarate

by Phyllis

Is there any benefit in taking Calcium D-Glucarate while using Progesterone cream?

Thank you and I look forward to your reply.

Comments for Calcium D-Glucarate

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Jan 30, 2011
Calcium D-Glucarate
by: Wray

Hi Phyllis Yes I believe there is a benefit. Oestrogen is metabolised in the liver by glucuronic acid, the process is known as glucuronidation. The process also removes other substances, including toxins, drugs, bilirubin, androgens, mineralocorticoids and glucocorticoids. It's then excreted in the bile, but an enzyme in the intestine called beta-glucuronidase breaks the oestrogen/glucuronide bond, which allows oestrogen to be reabsorbed. Calcium D-glucarate inhibits beta-glucuronidase. There's evidence beta-glucuronidase activity is increased in breast and prostate cancer, see here, here and here. Some fruits and vegetables contain it naturally, see here. Another study found that a diet containing fruits and vegetables didn't reduce beta-glucuronidase activity, in fact increased it, see here. Although there's no doubt supplementing with calcium D-glucarate does reduce beta-glucuronidase. Incidentally this enzyme is produced by undesirable gut bacteria, supplementing with probiotics suppresses the bacteria, and subsequently the beta-glucuronidase. Take care Wray

Feb 05, 2011
A Thank You
by: Phyllis

Hello Wray,
Thank you so much. Your reply was loaded with some valuable info. I'll be sure to continue taking my probiotics. I'm also consuming a drink made with unpasteurized honey, apple cider vinegar, lemon juice and ginger- small amount each day. My thinking is to use something that would benefit many organs at the same time and with the lemon juice acting on the liver, this should keep it in top shape for a while to come.

Again, thank you.

Feb 20, 2011
A Thank You
by: Wray

Hi Phyllis I'm pleased it helped you! I love the drink you mention, and go through phases of taking it, then forgetting. At the moment I'm drinking kombucha vinegar which we make. I'm not sure how beneficial this is, as opposed to the drink which is only mildly acidic. I will see! Pleased you're also taking probiotics, excellent stuff. Take care Wray

Feb 21, 2011
A Reply
by: Phyllis

Morning Wray,
I didn't know much about kombucha vinegar and did a research which was interesting. Perhaps you would also like this: Beets, carrots, ginger (I love ginger. I even make a ginger wine for a winter drink) and lemons. Liquefy the solids in the lemon juice, which will actually start a fermentation of the glucose in the vegetables after about 3 days. It must be refrigated when the liquid separates from the solids and will keep for ages thereafter. BE WARNED this drink may cause some of your bowel movements -for a while- to require a gas mask. Peace to you and enjoy your day, Phyllis

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