Hi Wray! I have so appreciated your site and all the help it's been to me as I'm trying to navigate this hormone issue. My issues with anxiety began about 6-7 years ago. I'm 37 and have 5 children. My last three were born in 3.5 years. The pregnancies with them were extremely stressful on my body and I suffered from severe hyperemesis. After the birth if my third child I just didn't feel 'right' and I became anxious and depressed. I chalked it up to sleep deprivation and life with a new baby. After my fourth child was born just 17 months later I hit rock bottom. After suffering for months I decided to go on Zoloft. It worked and life was good again. Then I got pregnant again. Nothing has been the same - I just keep spiraling in anxiety. Between pregnancy, nursing and the demands of life with five children everything sort of fell apart about 18 months ago. My youngest is almost 3 and I would have thought that my hormones would be back to normal but they aren't. My periods used to always be 30 days, very predictable. When this bout of anxiety hit so hard I started having 24-26 day cycles and spotting starting around 4-5 days out. I have tried several anti-depressants and anti-anxiety medications but really never found relief like I did after the birth if my fourth child. I began to search out natural remedies for anxiety and I came across progesterone. Everything I read screamed THIS IS ME!! I bought some (Emerita Pro-Gest 450 mg, 20mg/1/4 tsp) and started using it January 22, day 7 of my cycle, twice a day as recommended on the packaging. I noticed an immediate difference! I was still very anxious but it was more controllable, less intense. I stopped just as suggested too on day 28. My period didn't start again until day 38. By that time I had sunken back into the nasty pit of anxiety once again. I started using it again on day 4 of my cycle out of desperation (february 26). It again helped immediately...lessening the anxiety. I also started using a 1/8-1/4 tsp in the middle of the day and that made another big difference. I've been reading about your cream and I'm going to order it. I'm very concerned that I'm going to stop again on day 28 and spiral down again into another anxious pit. Do you have any suggestions or recommendations? I would appreciate any help or thoughts! Thank you so much in advance! I believe I'm onto something with the cream but I'm just not sure that I'm using it properly and getting the most benefit from it. Any help is appreciated! Thank you!! Blessings!!!