Adenomyosis and Progesterone Dosage

by Georgia

I went off the pill (after 10 years) at age 40 to try for a baby. After two miscarriages, I had a textbook pregnancy and delivered my little girl (now 9) at 42. I decided not to go back on the pill as there was only really one week out of the month we needed to be careful and I had always experienced painful ovulation, so knew exactly when it would happen.

My periods have become heavier in the last 4-5 years but these years have been accompanied by unbelievable stress - loss of a business, the death of my mother, moving countries and losing a house deposit.

Heavy, heavy periods and a bout of mid cycle bleeding made me go to the doctor and they diagnosed the beginnings of adenomyosis, along with 2 small uterine cysts and a 1cm uterine fibroid.

I have tried to clean up my exposure to xeno-estrogens, eat well, exercise and thankfully, stress levels are much lower.

All my tests were normal except my iron levels were low (hardly surprising), my testosterone was slightly elevated and my vitamin d was 97 nmol/L. I was tested on day 21 of my cycle and my results were:

FSH 6.0 U/L
LH 17.3 U/L
Oestradiol 1024 pmol/L
Progesterone 2.0 nmol/L

I immediately started taking 5000 iu of vitamin d, plus 2000mg of taurine and NAC as suggested, magnesium citrate, B complex, and 3-6mg of iodoral.

I also started taking natural progesterone this month on day 6 of my cycle but I'm now getting brown discharge on day 16. Obviously I didn't ovulate, but I'm unsure whether to increase the dose beyond 200mg as any more makes me wake up HOT. This is not a hot flush, sweaty kind of hot, just a raised body temperature, but I was sick of it interfering with my sleep so I reduced the dose and I'm sleeping fine again.

I know I must be in peri-menopause but to date, I have not experienced any hot flushes and now that I'm no longer super stressed I feel great. My mother went through menopause at 57 but the thought of having another 6 years of heavy periods does not thrill me. My Gynae has recommended a uterine ablation which I'm very tempted by.

I have read all the relevant pages on the site, so any additional advice about progesterone dosage would be greatly appreciated. Many thanks

Comments for Adenomyosis and Progesterone Dosage

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Sep 18, 2018
Adenomyosis and Progesterone Dosage
by: Joy

Hi Georgia

Adenomyosis is very similar to Endometriosis and is caused by oxidative stress, the same applies to Fibroids. You are in Peri-Menopause when monthly periods can become heavy, continual and erratic. The following protocol has helped many women who experience heavy bleeding, it will also help with fibroids adenomyosis/endometriosis.

* 400-500mg Natpro Progesterone Cream per day
* 2000mg N-Acetyl-Cysteine (NAC) per day
* 2000mg Taurine per day
* 5000iu's Vitamin D per day - more if deficient
* 1000mg Bioflavanoids per day

Usually 100-200mg progesterone is recommended but you need to use more to help with the heavy bleeding. Once that is under control you can slowly reduce the amount of progesterone. It is best to use progesterone every day with no breaks until things return to normal however, women in Peri-Menopause benefit by using it every day. Please read How to use Progesterone Cream and Estrogen Dominance. Progesterone therapy is not an overnight fix, it can take 2-6 months for the body to adjust.

I am pleased that you are now taking vitamin D3 as it is very important. A deficiency reduces the benefits of progesterone, optimal range is between 70-100ng/mL. Nothing less than 5,000iu's is needed daily. Co-factors are needed when taking D3, magnesium and vitamin K2 with no soy are the important ones.

Sep 27, 2018
by: Anonymous

Hi, thanks for your comments. Really not sure what to do after this first month using progesterone oil.

As suggested for adenomyosis, I started using the oil on day 6 of my cycle. At the suggested dosage, I was waking up hot in the middle of the night, so I reduced the dosage and this fixed the problem.

However, I obviously was no longer taking enough to hinder ovulation, as I ovulated yesterday - which was day 25 of my cycle. I was gearing up to get my period - not ovulate!

So, not sure whether I will get a full luteal phase now or whether I will start my period as technically it is due. This is an aspect of taking progesterone that I don't like. It is so hit and miss, especially with each person being unique and their body's reacting in different ways to different amounts.

So, how to proceed - I don't know. I suspect I might see how my next period goes, and try the progesterone AFTER ovulation.

Oct 01, 2018
by: Joy

Hi there. Progesterone therapy is not an overnight fix, it can take 2-6 months before one notices a change. You need to experiment to see what is best for you, as you say, we are all different. I also feel that you should be using progesterone every day with no breaks until things improve. Once they do, you can then use by following your cycle as explained on the How to use Progesterone Cream page.

You might also consider switching to a progesterone cream rather than an oil as it is the best Delivery Method.

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