34, no period, estrogen dominate with little to no progesterone

by Angella

HI! So thankful for this site.
I'm 34- No period, with vaginal atrophy. Its AWFUL!!!!
This led me to have my labs done and I'm producing little to no progesterone, and very little estrogen but still classifies me as estrogen dominant. I'm super fit and active and have not had a cycle in over a year.

Based on my labs the MD put me on a 75mg progesterone pill and I gained weight RAPIDLY (8lbs in a couple months) I had mood swings, emotional crying fits, water retention, swollen ankles, headaches (all day, everyday)

When I called the MD they said this was a "PARADAXICAL" effect of the progesterone and advised me to stop it temporarily and increase my bio-identical testosterone cream.

I'm a mess emotionally, I have discontinued use of all HRT and started taking a DIM supp for the dominance. I'm still dealing with the vaginal atrophy.

I'm struggling. Please help a sista out.

Comments for 34, no period, estrogen dominate with little to no progesterone

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Apr 17, 2018
34, no period, estrogen dominate with little to no progesterone
by: Joy

Hi Angella

Usually a missed period for 12 months puts one in menopause but you are too young for that. You could be suffering from amenorrhoea which is the absence of the menstruation cycle.

A good progesterone cream such as Natpro will help with your atrophy when inserted in the vagina at night. You have been given an oral progesterone which is the least effective as 96% gets destroyed by the gut and liver. The amount given is just enough to aggravate your estrogen receptors which is causing water retention etc. Please consider using a progesterone cream. Between 100-200mg is needed and should be used no less than twice a day.

We all suffer from estrogen dominance because there are well over 100 estrogen mimics in our environment today.

Please read these pages.

How to use Progesterone Cream -

Estrogen Dominance -

Delivery Methods -

Menstruation Cycle -

Environmental Toxins -

Apr 17, 2018
no period, estrogen dominance
by: Anonymous

What a terrible time for you, but there is hope getting all this right. You have come to the right site to help you.

First of all, the amount of progesterone prescribed is far too low and it is the wrong form to be taking it: orally. Orally is not the best way. In fact, most of the progesterone will be destroyed. Creams applied topically are the best, or suppositories, not orally. You need between 100mg - 200mg or more when symptoms are severe.

Initially when increasing progesterone the symptoms will appear increased, but that is because the progesterone needs to become the dominant hormone. Persevere! Many women panic and reduce the amount of progesterone or stop it altogether. Big mistake. More is needed.

Please put your questions into the search bar and you will read answers by Wray Whyte, who sadly is no longer with us. Read the information about "what is progesterone". All is here on this website but you need to do the reading. Don't just rely on putting a question out there and expect others to answer it. People will try to help as and when they can, as I am doing now. Educate yourself. This site provides information researched over many years by Wray Whyte.

Most doctors haven't a clue about women's hormones. They more often than not prescribe far too little progesterone, and in the wrong form - orally - and women just feel worse and give up. Don't give up. Increase your progesterone topically via a cream such as Natpro. At least 100mg to begin and if symptoms get worse, INCREASE the amount don't decrease. Eventually you will feel yourself again.

I personally take 400mg daily. I am an older woman but this amount for me I enjoy taking. It helps with flashes, body aches, sleep, the list of its benefits goes on and on.

I wish you all the best!

Apr 17, 2018
by: Angella


Thank you for your insight. I knew my symptoms are NOT normal. I will get her to change me to a cream as you suggested...would I put all of the dose in vaginally? or some on the skin and some in the vagina?

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